… to automate quantification of emphysema and air trapping … disease severity. We then
assessed the ability of our CT-based criteria to prognosticate disease progression and mortality…

… counts were useful in predicting disease severity and clinical … increase correlated with
disease severity. Secondary bacterial … , asthma, and chronic obstructive pulmonary disease were …

… Moreover, studies showed a positive relationship between disease severity and high
MUC5AC levels [59]. The results of pulmonary function tests revealed an inverse relationship …

… outlines the characteristics of useful biomarkers while highlighting some of the challenges
of biomarker research in a complex disease, such as COPD. … Surrogate for disease severity …

… of systemic biomarkers for … of multiple candidates for surrogate markers of disease activity
in a large, well-characterised cohort of COPD patients with varying degrees of disease severity …

… The results suggested that the dysregulation of several phagocytosis-related … COPD
patients was correlated to the level of obstruction and disease severity, as well as emphysema in …

… biomarkers. This review focuses on protein biomarkers associated with clinically relevant
COPD outcomes. The prototypic COPD protein biomarker is alpha-1 antitrypsin; however, this …

… of progression used to assess COPD progression have not been previously reported. This
finding emphasises the fact that disease activity and disease severity … patients with COPD.1 44 …

… significance of increased emphysema severity, as graded by a deep learning algorithm on
sequential CT scans according to the Fleischner Society emphysema classification system in …

… To our knowledge, this is the first study to investigate and validate CT biomarkers for
predicting severe exacerbations of COPD. We also showed that these biomarkers can be used to …