… CK1α and CK2 are overactive in multiple myeloma, … In humans, protein kinase CK2 exists
as a tetrameric enzyme, … in cancer cell biology, tumor cell survival and clonal expansion rely on …

… that the S/T kinase CK1α sustains MM cell survival through the … cells treated with Lena could
depend, also, on an active p53 … Our data suggest that protein kinase CK1α is a key regulator …

… cells has further demonstrated that activity from a CK2 catalytic subunit is necessary for cell
survival… in conjunction with the consistent reliance of cancer cells on elevated CK2 levels has …

… It has been determined that there are protein kinases that support the growth of malignant
plasma cells, and studies on these protein kinases have begun. Protein kinases cause …

… even demonstrated that protein kinase CK2 subunits are … heavily rely on CK2 activity/expression
for survival [Citation34… tumor cell survival and enhances HIF-1 transcriptional activity …

… CK2 potentiates each signal depends of course on its expression/activity level, becoming
prominent in cancer cells… , 11,88 and multiple myeloma. Several reviews summarize the …

… contributes to cell survival, proliferation and inflammation. … levels in multiple myeloma and
mantle cell lymphoma cells as … The development of ATP-competitive CK2 inhibitors is based …

… Protein kinase CK2 has been found to be well associated with several … CK2 regulates the
transcriptional activity of NF-κB signal by degrading its IκBα subunits in multiple myeloma cells. …

… , multiple myeloma and non-Hodgkin lymphomas (15–18). … Cell viability was measured
through Trypan blue exclusion … In this work, we characterized the role of protein kinase CK2 …

… Casein Kinase 2 (CK2), a protein kinase, has a multitasking function in the … surprising that
multiple myeloma cell survival relies on high activity of CK2 [96]. It has been shown that CK2 is …