… , multiple myeloma and non-Hodgkin lymphomas (15–18). … Cell viability was measured
through Trypan blue exclusion … In this work, we characterized the role of protein kinase CK2 …

… cells rely on high expression of replication related proteins … has described the role of protein
kinase CK1α and CK1δ in the … stress management for myeloma cell survival. Cottini et al. (…

… a particularly strong reliance on increased eIF4F activity for … The role of protein kinase CK2
in the process of proper B cell … Fifth, CK2 is essential for cell viability, and currently, there …

… in inhibiting CK2, displaying reduction of cell viability, decreased cell … Protein kinases are a
set of enzymes that catalyze the … associated tyrosine kinases) by OSM is dependent on CK2, …

… sustains prosurvival and proliferative signaling cascades that depend on NF-κB, PI3K/AKT/…
cycling under homeostatic conditions, we next analyzed cell survival. Splenic FoB and MZB …

… that depend on high levels of CK2 (EC 50 = 6.19 μM) by … Compound 64 influenced cell
viability by inducing apoptosis, … , LA Unique activation mechanism of protein kinase CK2. The N-…

… stromal cells (BMSCs), a hallmark of MM progression, is based … -22 activates JAK1,
tyrosine-protein kinase (Tyk)2 and MAPK … of cell survival, angiogenesis and tumor progression …

… that CK2 kinase supports CML cell viability even in cells with … that in resistant cells, CK2
activity is dependent on that of … Pharmacological inhibition of protein kinase CK2 reverts the …

… -CK2-1) as a highly potent and cell-active CK2 chemical probe with exclusive selectivity for
both human CK2 … of protein kinase CK2 inhibitors in clinical trials for the treatment of cancer. …

… in cell cycle, DNA damage response, or cell survival pathways, … antiapoptotic proteins
of the BCL-2 family, MM cells depend … 6 (ATF6), protein kinase R (PKR)-like ER kinase (PERK)-…