… The inhibitory effects of CDKs inhibitors depend … cells, cell survival, mitogenesis, and cell
differentiation. Any perturbation in the RTK signaling pathway can cause deregulation of activity …

… cell lines, showed that they are essential for the cell viability … role of WEE1 were obtained
in multiple myeloma (MM), acute … The mechanism of action of the combination is based on the …

… contains 518 protein kinases accounting for 1.7% of all human genes. (1) Kinases control a
… We stress that our evaluation is based on the total ligand–residue interactions. Consequently…

… It was the introduction of large panels of protein kinases to … and in multiple myeloma
harbouring various RAS–RAF mutations 61 . … This is based on two recent randomized studies …

… of function it performs depend on the type of cells and their … in T cells activates the
stress-activated protein kinase (SAPK)/… has no effect on cell viability or cell cycle progression [180]. …

… that protein kinase CK2 phosphorylates many viral proteins … in the regulation of cell survival
proliferation, gene expression … According to the study, cellular activity of CK2 depends on the …

… family of serine/threonine protein kinases that become active upon … DNA sequences is
dependent on the viral Tat protein that … CDK11 expression as essential for cell survival [94]. This …

… associated with cancer cell survival and growth such as … -3 cells while activation of p38
MAPK and protein kinase D1 … and cell recovery as well which does not depend necessarily …

… -activated protein kinase/extracellular signal-regulated kinase 1 … of cell proliferation, cell
survival, cell differentiation, cell … that rely on direct phosphorylation of ERK and those that rely on …

… The protein kinase CK2 is one of the most important … CK2 promotes cell survival, proliferation,
and angiogenesis and … The design of the ATP-competitive type I inhibitors relied on three …