… protein kinase with significant homology to eukaryotic kinases that are known regulate cell
… promote or inhibit tumor growth and survival in these roles depends on the cellular context. …

… in LNCaP cells is essential for cell survival since apoptosis … The protein kinase CK2 (formerly
known as casein kinase 2) … Tumor cells tend to depend on CK2 activity for their survival, …

… in multiple myeloma, anaplastic large-cell lymphoma, and … inhibitors rely on expression of
downstream signaling protein … reduces cell viability, induces apoptosis and cell cycle arrest in …

… and chronic leukemias, multiple myeloma and different types of … Drug resistance and increased
cancer cell survival are the main … A different type of modification relied on improving the …

… act at the intersection of cell survival and cell death, mounting … of Pink1, a serine/threonine
protein kinase that functions as a … , which is dependent on pyruvate dehydrogenase kinase 2 (…

… In ovarian cancer, multiple myeloma (MM), and head and … This leads to increased cell
survival, adhesion, motility and … of pancreatic cancer cells, which is dependent on CDK5. …

… relief and the refolding of denatured proteins [1]. When a host … A number of protein kinases
have been implicated in the … been shown to reduce cell viability in multiple myeloma, pleural …

… of high concentration of nutrients, phosphorylates ribosomal protein S6 kinase beta 1 (S6K1),
a protein kinase … phosphorylation and, therefore, rely on high levels of aerobic glycolysis as …

… line sensitivity to silmitasertib or dinaciclib did not depend on … CK2 is not the only protein
kinase that plays a critical role in … results suggest that dinaciclib inhibited cell viability at very low …

… Significantly, human primary multiple myeloma expressed … and survival of many myeloma
cells depend on the expression of FBXO9. Therefore, knockdown of the Tel2 and Tti1 proteins, …