Influence of carnitine isoforms and curcumin in models of Alzheimer's disease-Role of encapsulation in a nanoformulation

BJR Figueiredo - 2022 - estudogeral.uc.pt
Alzheimers disease (AD) is the leading cause of dementia … combined with CUR in rat cortical
neurons exposed to AβO1-… and also lower density of muscarinic ACh receptors. Furthermore…

[HTML][HTML] … docking and dynamic simulation of anti-cholinesterase compounds from the extract of Catunaregam spinosa for possible treatment of Alzheimer's disease

S Thandivel, P Rajan, T Gunasekar, A Arjunan, S Khute… - Heliyon, 2024 - cell.com
… This loss is linked to cortical cholinergic axons and cholinoceptive neurons, while
cholinesterase activity emerges in AD cortex, linked to plaques, tangles, and amyloid angiopathy. …

The Role of the Cholinergic System in Lung Diseases

V Milankovic, T Lazarevic-Pasti - … Signalling Pathways in Lung Diseases, 2021 - Springer
… AChE is consistently associated with both cholinergic and cholinoceptive neurons. At the …
and released by neuronal and non-neuronal sources and their action on muscarinic receptors. …

Role of the locus coeruleus and basal forebrain in arousal and attention

EB Maness, JA Burk, JT McKenna, FL Schiffino… - Brain research …, 2022 - Elsevier
… depolarize cortical interneurons, and G protein-coupled muscarinic … of cholinoceptive cortical
and thalamocortical neurons is … -cortical interactions of the frontal lobe with primary sensory …

[HTML][HTML] CSF and plasma cholinergic markers in patients with cognitive impairment

A Karami, T Darreh-Shori, M Schultzberg… - Frontiers in Aging …, 2021 - frontiersin.org
neurons and that stimulates a diverse array of muscarinic and … Early findings of the loss of
cholinergic neurons and marked … first drugs available for pharmacological treatment of AD, the …

Potential Cardiologic Protective Effects of Acetylcholinesterase Inhibitors in Patients With Mild to Moderate Dementia

L Rampa, R Santangelo, C Gaspardone… - The American Journal of …, 2023 - Elsevier
… because of the peripheral muscarinic M2 receptor stimulation. … neurons from the nucleus
basalis of Meynert 5 is associated with the cognitive impairment observed in Alzheimer disease (…

Neural Circuits for Sleep–Wake Regulation

Y Wu, L Wang, F Yang, W Xi - Neural Circuits of Innate Behaviors, 2020 - Springer
… Subtypes of nicotinic and muscarinic receptors in the hippocampus … neurons consist of
either direct projections to entorhinal cortex and prefrontal cortex or indirect projections to cortex

Tacr1 marks a population of long-range inhibitory neurons that regulate neurovascular coupling

CF Ruff - 2021 - search.proquest.com
… Human prefrontal cortex (postmortem delay 2 h) was … suggests that the cholinoceptive NO
neurons in this report … activation of these cortical Nos1 neurons via muscarinic acetylcholine (…

[图书][B] CNS Neurotransmitters and Neuromodulators: Acetylcholine

TW Stone - 2020 - books.google.com
… , and muscarinic binding sites) in the cerebral cortex was … 30% of neocortical neurons is
cholinoceptive, and for most of … of its degeneration in Alzheimer's disease and the dementia …

[HTML][HTML] The Mixture of Gastrodia elata and Glycyrrhiza uralensis Attenuates Scopolamine-Induced Cognitive Disorder

JH Lee, SW Kim, SH Lee, JY Cho, SH Hwang… - Applied Sciences, 2023 - mdpi.com
… and Alzheimer’s disease (AD) models [12]. Scopolamine leads to neurocognitive disease
by competitively blocking muscarinic acetylcholine (ACh) receptors and neuronal signal …