Whole genome phylogenies reflect the distributions of recombination rates for many bacterial species
… wide range of recombination to mutation rates from ρ / … recombination rates vary over a
wide range across different lineages, so that it is inherently misleading to quantify recombination …
wide range across different lineages, so that it is inherently misleading to quantify recombination …
Patterns of genetic variability in genomic regions with low rates of recombination
H Becher, BC Jackson, B Charlesworth - Current Biology, 2020 - cell.com
… The relation between recombination rate and patterns of … a low recombination region but
some weakly selected mutations cause … 4-fold degenerate variant sites on chromosome 4 for the …
some weakly selected mutations cause … 4-fold degenerate variant sites on chromosome 4 for the …
Divergent Evolution of Mutation Rates and Biases in the Long-Term Evolution Experiment with Escherichia coli
R Maddamsetti, NA Grant - Genome biology and evolution, 2020 - academic.oup.com
… Bacteria often evolve elevated mutation rates during … known about how mutation rates vary
over the chromosome, and … selection adaptively tunes mutation and recombination rates. This …
over the chromosome, and … selection adaptively tunes mutation and recombination rates. This …
Core genes can have higher recombination rates than accessory genes within global microbial populations
AP Steinberg, M Lin, E Kussell - Elife, 2022 - elifesciences.org
… is higher for the core genome, the mutational divergence is lower, indicating that … of bacterial
genomes. This paper addresses how the rate of homologous recombination varies between …
genomes. This paper addresses how the rate of homologous recombination varies between …
Two mechanisms of chromosome fragility at replication-termination sites in bacteria
… show elevated homologous recombination between plasmids and the chromosome (14). …
between the two types of fragile sites is suggested. Chromosome-resolution mutants, which …
between the two types of fragile sites is suggested. Chromosome-resolution mutants, which …
[HTML][HTML] Increased mutation rate is linked to genome reduction in prokaryotes
… by selection and the mutation rate. By comparing rates of gene loss with d N and d S across
a phylogeny, we can assess the relative importance of changes in N e , mutation rate, and …
a phylogeny, we can assess the relative importance of changes in N e , mutation rate, and …
Site-specific recombination–how simple DNA inversions produce complex phenotypic heterogeneity in bacterial populations
D Trzilova, R Tamayo - Trends in Genetics, 2021 - cell.com
… Phase variation can occur through multiple genetic and epigenetic mechanisms. This
review focuses on conservative site-specific recombination that generates reversible DNA …
review focuses on conservative site-specific recombination that generates reversible DNA …
Mechanisms for chromosome segregation in bacteria
… The roles of SMCs in organizing and segregating the bacterial chromosomes. (A) Time-lapse
images of a single SMC complex (yellow arrow) that extrudes a DNA loop in vitro. From …
images of a single SMC complex (yellow arrow) that extrudes a DNA loop in vitro. From …
Current methods for recombination detection in bacteria
… of calculation that assumes mutation rates to remain constant for each gene within a genome
[… result reflecting the recombination rate, however, the congruity between this method and …
[… result reflecting the recombination rate, however, the congruity between this method and …
Bacterial phenotypic heterogeneity in DNA repair and mutagenesis
MS Vincent, S Uphoff - Biochemical Society Transactions, 2020 - portlandpress.com
… bacteria, DSB repair and the replication cycle are closely connected, as HR is restricted to
regions of the chromosome … on mutation rates in bacteria has long been a very complex task …
regions of the chromosome … on mutation rates in bacteria has long been a very complex task …