… Univariate analysis revealed a trend for smoking history, negative HPV16 status and
lymph … Most subgroups of the TCGA-HNSC cohort based on risk factor stratification shared …

… 28 or tobacco smoke- related mechanisms of mutations, 29 … Simple main effect analysis
showed that mutational status … In particular, our classifier was able to better stratify a cohort …

… for high‐frequency mutations, we evaluated the somatic mutation profile of top10 most …
smoking status of tumor samples was associated with reduced interferon‐induced immune cell …

… which persisted in multivariate analysis included p16 status. O'… Patients were stratified by
multiple thresholds of smoking … deconstructSigs to perform mutational analysis based on C to …

… status by using the Evolutionary Action score of TP53-coding variants (EAp53) to stratify
patients with tumors harboring TP53 mutations … in our study, tobacco smoking was significantly …

… least 5% of patients (mutations in >10 cases) and with at least 50% of mutations assigned as
likely … differences by mutation status were assessed using Kaplan–Meier analysis and Cox-…

… tumor tissues, which indicated that the TP53 mutation status may influence the immune
response to HNSC. In the re-analysis, … eliminated for differential expression analysis. The results …

… Other factors, such as the tumor mutational burden and the … independent of the viral status
but smoking could not predict … improve current risk stratification for patients with OPSCC [109]. …

… efficacy and predicting risk stratification by identifying mutated … somatic mutation profiles,
CCRT response, and RFS status, we … to The Cancer Genome Atlas (TCGA) data, most smoking-…

… For this reason, we proposed a study of the mutational status … factors such as tobacco smoking
and alcohol consumption … Neskey’s classifications stratifying the mutations according to its …