Progress towards non-small-cell lung cancer models that represent clinical evolutionary trajectories

RE Hynds, KK Frese, DR Pearce… - Open …, 2021 - royalsocietypublishing.org
… cells or cells within bronchioalveolar duct junctions, whereas … of oncogenic driver mutations
in KRAS, EGFR, HER2, MET … and adenocarcinomas, while Trp53 mutations are found in …

[HTML][HTML] Daily Practice Assessment of KRAS Status in NSCLC Patients: A New Challenge for the Thoracic Pathologist Is Right around the Corner

C Bontoux, V Hofman, P Brest, M Ilié, B Mograbi… - Cancers, 2022 - mdpi.com
… % of lung adenocarcinomas and in around 5% to 7% of lung … needle aspiration,
bronchoalveolar lavage, pleural and … genes of interest (notably KRAS and HER2) are present in …

Molecular Pathogenesis, Organ Metastasis, and Targeted Therapy for Non-Small-Cell Lung Cancer

S Abdullah, R Chakraborty, PS Kumkar… - Journal of …, 2024 - dl.begellhouse.com
… of the primary tumor, such as mutations and gene amplification. … Her-2/neu receptor is an
erbB family tyrosine kinase receptoradenocarcinoma other than bronchioloalveolar carcinoma. …

[HTML][HTML] Liquid biopsies in lung cancer—a narrative review

PB Gahan, H Schwarzenbach - ExRNA, 2022 - exrna.amegroups.org
… In contrast, the NSCLC types are primarily adenocarcinomas, … (96,97) or lncRNAs (98)
present in bronchioalveolar lavage fluid (BALF) … In the FLAURA3 study, MET amplification, HER2

[HTML][HTML] … tumor DNA clearance predicts prognosis across treatment regimen in a large real-world longitudinally monitored advanced non-small cell lung cancer cohort

Y Song, C Hu, Z Xie, L Wu, Z Zhu, C Rao… - … Lung Cancer …, 2020 - ncbi.nlm.nih.gov
… 168 NSCLC-related genes on 949 advanced NSCLC patientsNSCLC (stage IIIB to IV)
patients with specific mutations in at … of patients, with all mutation clearance, only driver mutation

[HTML][HTML] Epidermal growth factor receptor expression and resistance patterns to targeted therapy in non-small cell lung cancer: A review

EA Karlsen, S Kahler, J Tefay, SR Joseph, F Simpson - Cells, 2021 - mdpi.com
Adenocarcinoma is the most common type of NSCLC, … : either a kinase-activating mutation
in EGFR (EGFR-mutant) or … For example, HER2 mutant or amplified tumours with bypass ERK …

Liquid Biopsy in non-small cell lung cancer: exosomes as a tool for the study of biomarkers.

ME Duréndez Sáez - 2024 - riunet.upv.es
… de Valencia HER2: human epidermal growth factor receptor 2 … The sub-classification of
lung adenocarcinomas has … , in which terms such as bronchoalveolar carcinoma (BAC) or the …

The effects of hypoxia on expression of stem cell markers in H1944 lung cancer cell line

MSM Al-Shamari - acikbilim.yok.gov.tr
… of mutations that cause a change in lung cancer described … of testing the HER2 mutation
in lung adenocarcinomas. The … of NSCLC are adenocarcinoma including Bronchioloalveolar

[HTML][HTML] Organoid based personalized medicine: from bench to bedside

Y Li, P Tang, S Cai, J Peng, G Hua - Cell Regeneration, 2020 - Springer
… of typical human normal colon epithelium, adenoma and adenocarcinoma organoids … to
study the mutational status of single stem cells. The gradual accumulation of genetic mutations in …

Molecular pathology of lung cancer

JJ Saller, TA Boyle - Cold Spring Harbor …, 2021 - perspectivesinmedicine.cshlp.org
lung adenocarcinoma (LUAD) as the most common histologic … patients with lung cancer
require knowledge about mutated … ERBB2 (HER2) up-regulation is typically associated with low …