… of peroxisome targeting signal 1 (PTS1) cargo protein, be monoubiquitinated and exported
back into the cytosol. Importantly, the mutant … a novel missense mutation in PEX5 responsible …

… to the second peroxisomal targeting signal (PTS1) is unclear. … biogenesis disorders, PBDs)
due to mutations in genes … as a cross-complementation between the mutation HS3E in the …

… is encoded by a single gene and imported into peroxisomes by the PTS1 receptor Pex5 in a
… by genetic phenotype-complementation assay with a peroxisome-defective CHO cell mutant…

… and implementing clinical biochemical genetic testing for peroxisomal disorders, …
Mutations in the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome …

… -terminal peroxisome-targeting signal (PTS1) that is defined … Mutations in the PEX genes
that affect peroxisome formation or the import of peroxisome matrix proteins cause peroxisome …

… the same group of disorders of peroxisomal biogenesis, but mutations in at least 13 PEX …
Mutations in the PTS1 receptor gene PXR1 define complementation group 2 of the peroxisome …

… shuttles between cytosol and peroxisomes and releases cargo … receptor and cargo release.
Our results reveal the unique mechanism by which PEX5 ferries proteins into peroxisomes…

… Here, we report that PTS1 shuttling receptor FvPex5 is involved in … deletion, we generated
a gene-complementation strain Δ… We suggest that the ΔFvpex5 mutant in F. verticillioides has …

… Mutations in the PTS1 receptor gene, PXR1, define complementation group 2 of the peroxisome
… PEX13 is mutated in complementation group 13 of the peroxisome-biogenesis disorders…

… Most matrix proteins use a C-terminal peroxisometargeting signal (PTS1) that is defined by
… a suppressor mutant in PEX1 that restored peroxisome function in a PEX6-defective mutant, …