Bone Loss in Intestinal Inflammation Disease Yields to Osteoclastogenesis Inhibition

W Strober - Cellular and Molecular Gastroenterology and …, 2022 - cmghjournal.org
Myeloid DAP12-associating lectin (MDL)-1 regulates synovial inflammation and bone
erosion … We hypothesized that intestinal inflammation leads to bone loss through increased …

Involvement of Siglec-15 in regulating RAP1/RAC signaling in cytoskeletal remodeling in osteoclasts mediated by macrophage colony-stimulating factor

H Kobayashi, MA Terkawi, M Ota, T Hasegawa… - Bone Research, 2024 - nature.com
lectin (Siglec)-15, triggering receptor expressed in myeloid cells (TREM-2) and myeloid
DAP12-associated lectin (MDL-1… development of inflammatory bone loss in inflammatory arthritis. …

Involvement of Siglec-15 in regulating RAP1/RAC signaling in cytoskeletal remodeling in osteoclasts mediated by macrophage colony-stimulating factor

M Takahata, H Kobayashi, M Ota, T Hasegawa… - 2023 - researchsquare.com
… cells (TREM-2) and myeloid DAP12-associated lectin (MDL-1) are to date known as … bone
resorption but plays a critical role in development of inflammatory bone loss in inflammatory

Intestinal inflammation promotes MDL-1+ osteoclast precursor expansion to trigger osteoclastogenesis and bone loss

CT Peek, CA Ford, KR Eichelberger, J Jacobse… - Cellular and Molecular …, 2022 - Elsevier
… an inflammation-induced osteoclast co-receptor, myeloid DNAX … lectin-1 (MDL-1) to reduce
bone loss during colitis. … potently regulates myelopoiesis, we evaluated changes in myeloid-…

[PDF][PDF] The impact of the C-type lectin receptor Mincle on osteoclast-mediated bone remodeling

D Andreev - 2020 - opus4.kobv.de
… that Mincle regulates osteoclastmediated bone remodeling by … Osteoclast progenitors
belong to the myeloid monocyte/ … by synovitis, an inflammation of the synovium that spreads to …

IL-23 induces CLEC5A+ IL-17A+ neutrophils and elicit skin inflammation associated with psoriatic arthritis

H Furuya, CT Nguyen, T Chan, AI Marusina… - Journal of …, 2024 - Elsevier
… of myeloid cell subsets that contribute to skin inflammation in … bone marrow and induces
Myeloid DAP12-associated lectinMDL-1 is a key regulator of synovial injury and bone erosion

Myeloid C-type lectin receptors in innate immune recognition

CR e Sousa, S Yamasaki, GD Brown - Immunity, 2024 - cell.com
… C-type lectin receptors (CLRs) expressed by myeloid cells constitute a versatile family of …
myeloid cell receptors are C-type lectin receptors (CLRs), part of the broader C-type lectin

Role of OSCAR signaling in osteoclastogenesis and bone disease

IR Nedeva, M Vitale, A Elson, JA Hoyland… - Frontiers in cell and …, 2021 - frontiersin.org
… pair with triggering receptor expressed on myeloid cells 2 (TREM2)… lectin 15 (Siglec-15), and
myeloid DAP12-associated lectin (… by inflammation of the synovial membranes, infiltration of …

[HTML][HTML] Current advances in regulation of bone homeostasis

AA Al‐Bari, A Al Mamun - Faseb Bioadvances, 2020 - ncbi.nlm.nih.gov
… , and myeloid DAP12associating lectin (MDL)‐1 associate with … the SASP, a pro‐inflammatory
environment. The SASP has … evidence that osteocyte regulates myeloid lineage cells (eg, …

Osteoclast signal transduction during bone metastasis formation

DS Győri, A Mócsai - Frontiers in cell and developmental biology, 2020 - frontiersin.org
loss during osteoporosis, inflammatory bone and joint … tightly regulated balance between
bone resorption and bone … -like lectin 15 (Siglec-15) and myeloid DAP12-associating lectin (…