[HTML][HTML] Therapeutic strategies for Duchenne muscular dystrophy: an update
… type of muscular dystrophy, Duchenne muscular dystrophy (DMD), is caused by mutations in
the X-linked dystrophin gene… Clinical data demonstrated that muscles treated with myoblast …
the X-linked dystrophin gene… Clinical data demonstrated that muscles treated with myoblast …
Transplantation of dystrophin expressing chimeric human cells of myoblast/mesenchymal stem cell origin improves function in Duchenne muscular dystrophy model
M Siemionow, E Szilagyi, J Cwykiel… - Stem cells and …, 2021 - liebertpub.com
… dystrophin expression correlating with improved function after transplantation of dystrophin
expressing chimeric (DEC) cells of myoblast … cell line of myoblasts and mesenchymal stem …
expressing chimeric (DEC) cells of myoblast … cell line of myoblasts and mesenchymal stem …
[HTML][HTML] Chimeric Cell Therapy Transfers Healthy Donor Mitochondria in Duchenne Muscular Dystrophy
M Siemionow, K Bocian, KT Bozyk, A Ziemiecka… - Stem Cell Reviews and …, 2024 - Springer
… myoblasts from both normal donor and Duchenne muscular … The fusion of myoblasts
mediated by polyethylene glycol (… at treating muscular dystrophies such as Duchenne muscular …
mediated by polyethylene glycol (… at treating muscular dystrophies such as Duchenne muscular …
Empowering muscle stem cells for the treatment of duchenne muscular dystrophy
RL Filippelli, NC Chang - Cells Tissues Organs, 2022 - karger.com
… effects on muscle health and is an underlying cause of muscle … cell dysfunction in Duchenne
muscular dystrophy (DMD), to … are transferred to DMD muscle tissue during myoblast fusion, …
muscular dystrophy (DMD), to … are transferred to DMD muscle tissue during myoblast fusion, …
Stem cell-based therapies for Duchenne muscular dystrophy
… cell transplantation and numerous efforts to optimize cell culture conditions in a lab setting,
the use of myoblasts or satellite cells to treat DMD in the clinic has not been realized yet. …
the use of myoblasts or satellite cells to treat DMD in the clinic has not been realized yet. …
[HTML][HTML] In utero transplantation of myoblasts and adipose-derived mesenchymal stem cells to murine models of Duchenne muscular dystrophy does not lead to …
Y Kihara, Y Tanaka, M Ikeda, J Homma, R Takagi… - Regenerative …, 2022 - Elsevier
… myoblast culture medium. Since Motohashi et al. reported that these myoblasts engrafted to
muscle … the same method, would also be able to engraft if they migrated into the muscle [45]. …
muscle … the same method, would also be able to engraft if they migrated into the muscle [45]. …
[HTML][HTML] Engraftment of human induced pluripotent stem cell-derived myogenic progenitors restores dystrophin in mice with duchenne muscular dystrophy
R He, H Li, L Wang, Y Li, Y Zhang, M Chen, Y Zhu… - Biological research, 2020 - Springer
… Duchenne muscular dystrophy (DMD) is a devastating genetic muscular disorder with no
effective treatment that … Researchers have shown that transplantation of myoblasts from healthy …
effective treatment that … Researchers have shown that transplantation of myoblasts from healthy …
[HTML][HTML] Muscle and cardiac therapeutic strategies for Duchenne muscular dystrophy: past, present, and future
A Łoboda, J Dulak - Pharmacological Reports, 2020 - Springer
… Duchenne muscular dystrophy (DMD) is a severe X-linked neuromuscular childhood
disorder that causes progressive muscle weakness and degeneration and results in functional …
disorder that causes progressive muscle weakness and degeneration and results in functional …
[HTML][HTML] … of bone marrow-MSCs and myogenic stem/progenitor cells from adult donors improves muscle function of patients with Duchenne muscular dystrophy
A Klimczak, A Zimna, A Malcher, U Kozlowska… - Cells, 2020 - mdpi.com
… muscle … muscle function using the transplanted myoblasts were explained by an inadequate
number and restricted distribution of the transplanted cells in skeletal muscles, as myoblasts …
number and restricted distribution of the transplanted cells in skeletal muscles, as myoblasts …
[HTML][HTML] Duchenne muscular dystrophy hiPSC–derived myoblast drug screen identifies compounds that ameliorate disease in mdx mice
C Sun, IY Choi, YIR Gonzalez, P Andersen… - JCI insight, 2020 - ncbi.nlm.nih.gov
… To test the feasibility of the compound screening format, we imaged myoblasts treated with
… of parameters after the treatment of gentamicin or vector DMSO on D2 myoblasts as a pilot …
… of parameters after the treatment of gentamicin or vector DMSO on D2 myoblasts as a pilot …