[HTML][HTML] Therapeutic strategies for Duchenne muscular dystrophy: an update

C Sun, L Shen, Z Zhang, X Xie - Genes, 2020 - mdpi.com
… type of muscular dystrophy, Duchenne muscular dystrophy (DMD), is caused by mutations in
the X-linked dystrophin gene… Clinical data demonstrated that muscles treated with myoblast

Transplantation of dystrophin expressing chimeric human cells of myoblast/mesenchymal stem cell origin improves function in Duchenne muscular dystrophy model

M Siemionow, E Szilagyi, J Cwykiel… - Stem cells and …, 2021 - liebertpub.com
dystrophin expression correlating with improved function after transplantation of dystrophin
expressing chimeric (DEC) cells of myoblast … cell line of myoblasts and mesenchymal stem …

[HTML][HTML] Chimeric Cell Therapy Transfers Healthy Donor Mitochondria in Duchenne Muscular Dystrophy

M Siemionow, K Bocian, KT Bozyk, A Ziemiecka… - Stem Cell Reviews and …, 2024 - Springer
myoblasts from both normal donor and Duchenne muscular … The fusion of myoblasts
mediated by polyethylene glycol (… at treating muscular dystrophies such as Duchenne muscular

Empowering muscle stem cells for the treatment of duchenne muscular dystrophy

RL Filippelli, NC Chang - Cells Tissues Organs, 2022 - karger.com
… effects on muscle health and is an underlying cause of muscle … cell dysfunction in Duchenne
muscular dystrophy (DMD), to … are transferred to DMD muscle tissue during myoblast fusion, …

Stem cell-based therapies for Duchenne muscular dystrophy

C Sun, C Serra, G Lee, KR Wagner - Experimental neurology, 2020 - Elsevier
… cell transplantation and numerous efforts to optimize cell culture conditions in a lab setting,
the use of myoblasts or satellite cells to treat DMD in the clinic has not been realized yet. …

[HTML][HTML] In utero transplantation of myoblasts and adipose-derived mesenchymal stem cells to murine models of Duchenne muscular dystrophy does not lead to …

Y Kihara, Y Tanaka, M Ikeda, J Homma, R Takagi… - Regenerative …, 2022 - Elsevier
myoblast culture medium. Since Motohashi et al. reported that these myoblasts engrafted to
muscle … the same method, would also be able to engraft if they migrated into the muscle [45]. …

[HTML][HTML] Engraftment of human induced pluripotent stem cell-derived myogenic progenitors restores dystrophin in mice with duchenne muscular dystrophy

R He, H Li, L Wang, Y Li, Y Zhang, M Chen, Y Zhu… - Biological research, 2020 - Springer
Duchenne muscular dystrophy (DMD) is a devastating genetic muscular disorder with no
effective treatment that … Researchers have shown that transplantation of myoblasts from healthy …

[HTML][HTML] Muscle and cardiac therapeutic strategies for Duchenne muscular dystrophy: past, present, and future

A Łoboda, J Dulak - Pharmacological Reports, 2020 - Springer
Duchenne muscular dystrophy (DMD) is a severe X-linked neuromuscular childhood
disorder that causes progressive muscle weakness and degeneration and results in functional …

[HTML][HTML] … of bone marrow-MSCs and myogenic stem/progenitor cells from adult donors improves muscle function of patients with Duchenne muscular dystrophy

A Klimczak, A Zimna, A Malcher, U Kozlowska… - Cells, 2020 - mdpi.com
musclemuscle function using the transplanted myoblasts were explained by an inadequate
number and restricted distribution of the transplanted cells in skeletal muscles, as myoblasts

[HTML][HTML] Duchenne muscular dystrophy hiPSC–derived myoblast drug screen identifies compounds that ameliorate disease in mdx mice

C Sun, IY Choi, YIR Gonzalez, P Andersen… - JCI insight, 2020 - ncbi.nlm.nih.gov
… To test the feasibility of the compound screening format, we imaged myoblasts treated with
… of parameters after the treatment of gentamicin or vector DMSO on D2 myoblasts as a pilot …