… Here, we investigated whether the NLRP3 inflammasome mediated Ang II-induced renal
fibrosis… , NLRP3 gene deletion attenuates Ang II-induced glomerular injury and renal fibrosis via …

… the cytosol to the mitochondria during hypoxia where it binds to mitochondrial antiviral …
The deletion of NLRP3 or MAVS in renal tubular cells attenuates mitochondrial ROS production …

… improved renal fibrosis by inhibiting the activation of NLRP3 … It has been reported that
NLRP3 deletion promoted … It has been reported that the inhibition of autophagy attenuates …

… Nlrp3 gene deletion attenuated mitochondrial abnormalities, … dysfunction and renal fibrosis
in a model of unilateral ureteral … , Nlrp3 -/- mice were protected against Ang II-induced Nlrp3 …

… reported to attenuate the development of renal fibrosis in mice [… of mitophagy in renal
fibrosis in UUO by deleting PINK1 or … injury by reducing mitochondrial dysfunction and NLRP3 …

… inflammasome inhibitors or genetic deletion of inflammasome components [20,21,22]. …
, NLRP3 depletion during rhabdomyolysis protects against renal injuries via attenuation of …

… of how CA attenuates the progression of renal fibrosis were investigated by targeting
NOX4 to mediate downstream signal routings, including NLRP3 inflammasome activation, …

… function, podocyte injury and renal fibrosis in db/db mice (33)… −/− mice, meanwhile, the
mitochondrial morphology and CKD… of NLRP3 inflammasome components as well as attenuated …

… Mitophagy, the removal of damaged or dysfunctional mitochondria, reduces ROS and …
reduce the activation of the NLRP3 inflammasome, significantly reducing renal fibrosis [101]. In …

… , and IL-1β receptor deficiency protects against mitochondrial dysfunction and NLRP3 …
could effectively attenuate hyperuricemia-induced CKD and renal fibrosis by inhibiting NLRP3 …