… injury and apoptosis by decreasing oxidative stress in a mouse … to the sites of infection or
tissue injury. Within the peripheral … NLRX1 dampens oxidative stress and apoptosis in tissue …

… impact of NLRX1/UQCRC2 on mitochondrial function has not … and CNS, NLRX1 may dampen
inflammatory responses by … intrinsic apoptosis regulation occurs via NLRX1 interactions …

… homeostasis and metabolic balance, as well as apoptosis and … The interaction between
oxidative stress and autophagy has … of NLRX1 in the regulation of mitochondrial function, and …

… and acts to dampen inflammatory responses, unlike the … and trafficking of NLRX1 to the
mitochondria is unknown. Further … NLRX1 was deemed essential for TNF-α-mediated apoptosis. …

… in mitochondria 8,9 . Recent research has shown that NLRX1 has roles in modulation of
mitochondrial function, … NLRX1 deficiency dampens the inflammation and mortality induced by …

… It has been found that NLRX1 depletion impaired lysosomal function and… NLRX1 can protect
tubular epithelial cells from mitochondrial damage and apoptosis through an oxidative stress…

… and PARP-1, we suggest an indirect action regulated by NLRX1 in the mitochondria to …
NLRX1 dampens oxidative stress and apoptosis in tissue injury via control of mitochondrial activity…

… from mitochondria that drive apoptosis include apoptosis-… in HG through increasing oxidative
stress and AMPK … viral infection, in which case NLRX1 dampens IFN signaling 279. MAVS …

… dependent extrinsic apoptosis induced by TNFα-cycloheximide … inflammation in different
models of tissue injury. The effect of … oxidative stress in kidney epithelial cells and loss of NLRX1 …

… , anti-inflammatory mitochondrial NLRX1, affects IRI and … This study demonstrated that
NLRX1 reduces apoptosis and … how NLRX1 regulates mitochondrial function. A general …