… In the present study, we identified empagliflozin as a novel suppressor of mitochondrial
fission during I/R-induced endothelial dysfunction. Thus, empagliflozin may be able to attenuate …

… H/R-induced cardiac damage via suppressing apoptosis, oxidative … ischemia reperfusion
injury through inhibition of pyroptosis … osteoarthritis through epigenetic control of NR4A1. Int. J. …

… for treating ischemic diseases, the reperfusion period aggravates the tissue injury. Moreover…
the Ca 2+ /CaMKKβ/AMPK pathway or by suppressing mTOR signal transduction. For …

… of Gr1 + neutrophils into the myocardium and therefore suppressed the transcription of … the
pathogenesis of cardiac microvasculature ischemia/reperfusion injury via induction of mROS-…

… of coronary microvascular damage during reperfusion injury … , nuclear receptor subfamily 4
group A member 1 (NR4A1) is … However, regardless of ischemia or reperfusion, suppression …

… in a mouse model of cardiac microvascular I/R injury, and genetic … activation of OPA1
suppresses mitochondrial fission and … otherwise accelerate or aggravate cardiomyocyte loss and …

… , while pro-inflammatory mediators are suppressed. Activated … to acute ischemia–reperfusion
injury by moderating the local … differentiated cardiac macrophages depend on Nr4a1 to limit …

… insights into the role of macrophages in diabetic microvascular … infarction, and myocardial
ischemia/reperfusion injury (96–98)… ISL mitigates diabetic cardiomyopathy by suppressing high …

… Microvascular damage is a key pathological change in myocardial ischemia/reperfusion (I/R)
injury. Using a rat model of myocardial I/R, our current study has provided the first evidence …

… that ATRA suppresses the calcification of coronary artery and … of superoxide dismutase and
aggravated by WY-14,643 treatment… damage in a model of cardiac microvascular I/R injury is …