Updated views on neutrophil responses in ischemiareperfusion injury

HM Shepherd, JM Gauthier, Y Terada, W Li… - …, 2022 - journals.lww.com
… lung procurement or by using donors deficient in NR4A1, a … activity of neutrophils through
ICAM-1 suppression. As such, … promoted autophagy and aggravated IRI-induced injury. In a …

[HTML][HTML] A comprehensive miRNome analysis of macrophages isolated from db/db mice and selected miRNAs involved in metabolic syndrome-associated cardiac …

J Niderla-Bielińska, A Ścieżyńska, A Moskalik… - International Journal of …, 2021 - mdpi.com
… the microvessel number in control animals (Figure 6e–g). Moreover, the inflammatory cell
profile assessed by flow cytometry analysis in cell suspensions obtained from cardiac tissue …

Role of mitophagy in myocardial ischemia/reperfusion injury and Chinese medicine treatment

J Xia, C Chen, Q Lin, J Cui, J Wan, Y Li, D Li - Chinese journal of …, 2023 - Springer
NR4A1 aggravates the cardiac microvascular ischemia reperfusion injury through suppressing
FUNDC1-mediated mitophagy and promoting Mff-required mitochondrial fission by CK2α…

[HTML][HTML] Transcriptional regulation of macrophages in heart failure

K Wang, X Sun, Y Sun, B Jiao, J Yao, Y Hu… - Frontiers in …, 2023 - frontiersin.org
cardiac output after dilated cardiomyopathy surgery, such as depressed coronary angiogenesis
and aggravated … and cardiac hypertrophy (68), thereby indicating that suppression of the …

[HTML][HTML] Molecular mechanisms of mitochondrial quality control in ischemic cardiomyopathy

X Chang, R Liu, R Li, Y Peng, P Zhu… - International Journal of …, 2023 - ncbi.nlm.nih.gov
… area, the myocardial injury caused by reperfusion injury may be … molecule that suppresses
cell death mediated via the … We also observed that in WT mouse endothelial cells, NR4A1

Mitophagy mediated by HIF-1α/FUNDC1 signaling in tubular cells protects against renal ischemia/reperfusion injury

W Zhang, C Guo, Y Li, H Wang, H Wang, Y Wang… - Renal …, 2024 - Taylor & Francis
… the effects of cardiac microvascular ischemia/reperfusion through FUNDC1-induced … kinase
1, NR4A1, and Ripk3, aggravate cardiac ischemia injury through suppression of FUNDC1-…

Role of non-myocyte NRG1/ERBB4 signaling in cardiac remodeling

L Dugaucquier - 2020 - repository.uantwerpen.be
… Neuregulin-1 suppresses the inflammatory response during … endothelium and cardiac
microvascular endothelium, and this … the heart against ischemia/reperfusion injury through a PI3K/…

Mitophagy alleviates ischemia/reperfusion-induced microvascular damage through improving mitochondrial quality control

D Wu, H Ji, W Du, L Ren, G Qian - Bioengineered, 2022 - Taylor & Francis
… cell inflammation, ischemia/reperfusion injury and insulin … microvascular endothelial cells,
thus aggravating coronary … -induced microvascular endothelial cell injury by suppressing

[HTML][HTML] SERCA overexpression reduces reperfusion-mediated cardiac microvascular damage through inhibition of the calcium/MCU/mPTP/necroptosis signaling …

C Li, Q Ma, S Toan, J Wang, H Zhou, J Liang - Redox biology, 2020 - Elsevier
… calcium overload, suppressed mitochondrial calcium uniporter (MCU… a post-ischemic
reperfusion attack. Overexpression of … or during reperfusion injury to reduce microvascular

[HTML][HTML] Phosphoglycerate mutase 5 exacerbates cardiac ischemia-reperfusion injury through disrupting mitochondrial quality control

H Zhu, Y Tan, W Du, Y Li, S Toan, D Mui, F Tian… - Redox biology, 2021 - Elsevier
… rescue suppressed mitophagy upon I/R injury. In conclusion, our results provide an insight
into … cardiomyocyte necroptosis through imposing mitochondrial quality control in cardiac I/R …