… Taken together, we have developed a flexible and versatile mRNA nanoparticle platform …
, AL Yu, alphaGalactosylceramide but not phenyl-glycolipids induced NKT cell anergy and IL-33…

… We developed an orally delivered nanoemulsion that induces … successfully induced OVA-
and α-GalCer-mediated activation … available nanoparticles for drug delivery, the use of such …

… NKT cell-activating nanoparticle-based vaccine delivery system was supported in order to
avoid the NKT cell anergy… the dendritic cells and activates iNKT cells without inducing anergy […

… We also feature new studies that suggest activating NKT cells can … , the vaccines activated
NKT cells without inducing anergy. … These nanoparticles were found to induce both cellular …

… gold nanoparticles was performed under gentle conditions, no … of the prepared vaccines to
induce the activation of DCs, the … reason was that NKT cell anergy might be induced when a …

… natural killer T (NKT) cell agonist alpha-galactosylceramide (α-… inactivated influenza virus
loaded nanoparticles and soluble α-… cells to become anergic, which occurs when NKT cells are …

… Type I NKT cells are commonly referred to as invariant NKT (… attributes of iNKT cell activity in
mice, including iNKT anergy, the … killer T-cell ligand alpha-galactosylceramide (KRN7000) in …

… -loaded nanoP significantly activate iNKT cells in vivo without inducing anergy, we next …
simultaneously in a nanoP formulation can induce B cell activation to generate a high-titer …

… A phase I study of the natural killer T-cell ligand alpha-galactosylceramide (KRN7000) in …
Nanoparticle formulated alpha-galactosylceramide activates NKT cells without inducing anergy…

… conditions for induction of both humoral and cellular immunity … lipoplexes (LPXs) or lipid
nanoparticles (LNPs) were evaluated … This phenomenon often referred to as iNKT cell anergy is …