[HTML][HTML] Dexamethasone-loaded ROS-responsive poly (thioketal) nanoparticles suppress inflammation and oxidative stress of acute lung injury
Z Zhai, W Ouyang, Y Yao, Y Zhang, H Zhang, F Xu… - Bioactive Materials, 2022 - Elsevier
… decreased lung inflammation, and reduced lung injury and … The intravenously injected
PTKNPs@Dex accumulate in lung, … , a lower level of cytokines and thereby reduced lung injury. …
PTKNPs@Dex accumulate in lung, … , a lower level of cytokines and thereby reduced lung injury. …
Role of oxidative stress in nanoparticles toxicity
… Oxidative stress plays a critical role in nanotoxicity. Various types of nanoparticles are known
to induce oxidative stress by … Cellular uptake of nanoparticles and intracellular metal ion …
to induce oxidative stress by … Cellular uptake of nanoparticles and intracellular metal ion …
Novel drug delivery systems targeting oxidative stress in chronic obstructive pulmonary disease: a review
Y Xu, H Liu, L Song - Journal of nanobiotechnology, 2020 - Springer
… oxide (IV) nanoparticles conjugated with the antioxidative … nanoparticles exhibit intrinsic
oxidant-generating properties. Some silver nanoparticles were found to induce oxidative stress …
oxidant-generating properties. Some silver nanoparticles were found to induce oxidative stress …
Nanomedicines targeting respiratory injuries for pulmonary disease management
… major respiratory injuries, acute lung injury, and acute respiratory … lipid nanoparticles, polymeric
nanoparticles, and inorganic … respiratory diseases symptom by reducing oxidative stress …
nanoparticles, and inorganic … respiratory diseases symptom by reducing oxidative stress …
ROS-responsive polymer nanoparticles with enhanced loading of dexamethasone effectively modulate the lung injury microenvironment
W Muhammad, J Zhu, Z Zhai, J Xie, J Zhou, X Feng… - Acta biomaterialia, 2022 - Elsevier
… oxidative stress [15]. Therefore, blocking the excessive level of ROS to alleviate oxidative
stress is a promising strategy to lessen lung … as scaffolds, hydrogels, and nanoparticles (NPs), …
stress is a promising strategy to lessen lung … as scaffolds, hydrogels, and nanoparticles (NPs), …
… silicon dioxide nanoparticles cause lung epithelial cells apoptosis via oxidative stress-activated PI3K/Akt-mediated mitochondria-and endoplasmic reticulum stress …
KI Lee, CC Su, KM Fang, CC Wu, CT Wu, YW Chen - Scientific reports, 2020 - nature.com
… cancer, emphysema, chronic obstructive pulmonary disease, or lung … oxidative stress and
activate apoptosis in human lung epithelial derived-A549 cells 16 . Induction of oxidative stress …
activate apoptosis in human lung epithelial derived-A549 cells 16 . Induction of oxidative stress …
TiO2 Nanoparticles Caused DNA Damage in Lung and Extra-Pulmonary Organs Through ROS-Activated FOXO3a Signaling Pathway After Intratracheal …
B Han, Z Pei, L Shi, Q Wang, C Li, B Zhang… - International Journal …, 2020 - Taylor & Francis
… In this study, a Nano-TiO 2 exposure rat model through tracheal perfusion was established
to evaluate the effects of Nano-TiO 2 on oxidative stress and DNA damage in the lung, liver, …
to evaluate the effects of Nano-TiO 2 on oxidative stress and DNA damage in the lung, liver, …
Attenuation of cigarette-smoke-induced oxidative stress, senescence, and inflammation by berberine-loaded liquid crystalline nanoparticles: in vitro study in 16HBE …
… for chronic obstructive pulmonary disease. Numerous toxicants present in cigarette smoke
are known to induce oxidative stress and airway inflammation that further exacerbate disease …
are known to induce oxidative stress and airway inflammation that further exacerbate disease …
Rutin loaded liquid crystalline nanoparticles inhibit lipopolysaccharide induced oxidative stress and apoptosis in bronchial epithelial cells in vitro
… for hydrophobic drugs, the present study was aimed to evaluate the effect of rutin-loaded
liquid crystalline nanoparticles on LPS induced oxidative stress in bronchoepithelial cells. …
liquid crystalline nanoparticles on LPS induced oxidative stress in bronchoepithelial cells. …
Oxidative stress-and mitochondrial dysfunction-mediated cytotoxicity by silica nanoparticle in lung epithelial cells from metabolomic perspective
X Zhao, A Abulikemu, S Lv, Y Qi, J Duan, J Zhang… - Chemosphere, 2021 - Elsevier
… Five metabolic pathways were significantly perturbed, in particular, oxidative stress- and …
Moreover, SiNPs triggered oxidative stress as confirmed by the dose-dependent ROS …
Moreover, SiNPs triggered oxidative stress as confirmed by the dose-dependent ROS …