Nanoparticles for antimicrobial agents delivery—an up-to-date review
DA Mercan, AG Niculescu, AM Grumezescu - International Journal of …, 2022 - mdpi.com
DA Mercan, AG Niculescu, AM Grumezescu
International Journal of Molecular Sciences, 2022•mdpi.comInfectious diseases constitute an increasing threat to public health and medical systems
worldwide. Particularly, the emergence of multidrug-resistant pathogens has left the
pharmaceutical arsenal unarmed to fight against such severe microbial infections. Thus, the
context has called for a paradigm shift in managing bacterial, fungal, viral, and parasitic
infections, leading to the collision of medicine with nanotechnology. As a result, renewed
research interest has been noted in utilizing various nanoparticles as drug delivery vehicles …
worldwide. Particularly, the emergence of multidrug-resistant pathogens has left the
pharmaceutical arsenal unarmed to fight against such severe microbial infections. Thus, the
context has called for a paradigm shift in managing bacterial, fungal, viral, and parasitic
infections, leading to the collision of medicine with nanotechnology. As a result, renewed
research interest has been noted in utilizing various nanoparticles as drug delivery vehicles …
Infectious diseases constitute an increasing threat to public health and medical systems worldwide. Particularly, the emergence of multidrug-resistant pathogens has left the pharmaceutical arsenal unarmed to fight against such severe microbial infections. Thus, the context has called for a paradigm shift in managing bacterial, fungal, viral, and parasitic infections, leading to the collision of medicine with nanotechnology. As a result, renewed research interest has been noted in utilizing various nanoparticles as drug delivery vehicles, aiming to overcome the limitations of current treatment options. In more detail, numerous studies have loaded natural and synthetic antimicrobial agents into different inorganic, lipid, and polymeric-based nanomaterials and tested them against clinically relevant pathogens. In this respect, this paper reviews the most recently reported successfully fabricated nanoformulations that demonstrated a great potential against bacteria, fungi, viruses, and parasites of interest for human medicine.
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