… systemic, microenvironmental and cellular — that are heterogeneous … that these medicines
will greatly influence precision NPs in the … Although local delivery methods may allow NPs to …

… Drug Administration [8]. Cytotoxicity and rapid clearance of most of the synthetic NDDS via
the mononuclear phagocyte system or reticuloendothelial system … to modify the nanoparticles (…

… The hydrophobic block will influence the stability and drug release characteristics, while
the … To proof nanoparticle uptake, the polymer should be labelled and colocalized with the …

… tissues and subsequently enter cells to modify crucial cellular functions, one of which is to
… cytotoxicity of the nanoparticle due to the influence of nanoparticle surface chemistry on its …

… or cellular process and the possibility to influence their functions [4]. Drug delivery systems
(DDS) … for drug delivery to the body with maximum benefit to risk ratio [5]. The development of …

… of in-vitro cellular toxicity when compared with nanoparticles that were … entrapment was
observed with functionalised nanoparticles. … nanoparticles are promising drug delivery system in …

… such as length, shape, and density of PEG chains affecting … phagocytic system and may
provoke cellular toxicity [260]. … be limited with nanoparticle-based drug delivery systems due to …

… As reported by Choi et al., the surface charge could be a major factor influencing the lymph
… to identify crucial cellular mechanisms involved in lung nanoparticle responses. Hydrogel …

… implants, wound dressings and drug delivery systems rely upon their effective interaction …
properties of nanomaterials that influence their cellular internalization, cytoplasmic transport…

… Current research into the role of engineered nanoparticles in drug delivery systems (DDSs)
for medical purposes has developed numerous fascinating nanocarriers. This paper reviews …