[HTML][HTML] Nanoparticles exhibiting virus-mimic surface topology for enhanced oral delivery
Z Sang, L Xu, R Ding, M Wang, X Yang, X Li… - Nature …, 2023 - nature.com
… of viruses to tissues and cells, we construct an efficient oral Nano-DDS … mimicking both the
structure and function of viruses. We first prepare mesoporous silica NPs with nanoscale virus-…
structure and function of viruses. We first prepare mesoporous silica NPs with nanoscale virus-…
Why synthetic virus-like nanoparticles can achieve higher cellular uptake efficiency?
… by mimicking the spiky surfaces of viruses; however, little is … as oral delivery vectors
with enhanced delivery efficiency. The … on how the virus-like surface topology affects NP–bilayer …
with enhanced delivery efficiency. The … on how the virus-like surface topology affects NP–bilayer …
[HTML][HTML] Bioinspired nanotopographical design of drug delivery systems
JA Finbloom, C Huynh, X Huang… - Nature Reviews …, 2023 - nature.com
… Virus-inspired topographical nanoneedles can improve … may better mimic the nanoneedle
injectors of natural viruses, … For example, virus-inspired mesoporous silica nanoparticles …
injectors of natural viruses, … For example, virus-inspired mesoporous silica nanoparticles …
Spiky nanostructures with geometry-matching topography for virus inhibition
C Nie, M Stadtmüller, H Yang, Y Xia, T Wolff… - Nano …, 2020 - ACS Publications
… better to virions than smooth nanoparticles, due to the … virus replication at the cellular nontoxic
dosage. We predict that such a combination of geometry-matching topography and cellular …
dosage. We predict that such a combination of geometry-matching topography and cellular …
Biomimetic nanomaterial strategies for virus targeting: Antiviral therapies and vaccines
JA Jackman, BK Yoon, L Ouyang… - Advanced Functional …, 2021 - Wiley Online Library
… vi) Biomimetic nanoparticle vaccines that mimic the … , targeted delivery, and/or improved
safety of viral replication inhibitors… A virus (IAV) particle based on geometry-matching topology. f) …
safety of viral replication inhibitors… A virus (IAV) particle based on geometry-matching topology. f) …
Biomimetic virus-like mesoporous silica nanoparticles improved cellular internalization for co-delivery of antigen and agonist to enhance Tumor immunotherapy
Y Gao, Y Zhang, H Xia, Y Ren, H Zhang, S Huang… - … delivery, 2023 - Taylor & Francis
… rough surface topology by mimicking the unique shapes and specific functions of viruses, …
-like VMSNs do have superior cell invasion ability and could fulfill the delivery task into cells …
-like VMSNs do have superior cell invasion ability and could fulfill the delivery task into cells …
[HTML][HTML] Biomaterials-based formulations and surfaces to combat viral infectious diseases
S Kumari, K Chatterjee - APL bioengineering, 2021 - pubs.aip.org
… viral infections. Relevant advances in biomaterials employed with nanotechnology to inactivate
viruses or to inhibit virus … surfaces through nanostructured topography and hydrophobic …
viruses or to inhibit virus … surfaces through nanostructured topography and hydrophobic …
Virus-mimicking mesoporous organosilica nanocapsules with soft framework and rough surface for enhanced cellular uptake and tumor penetration
… mimic virus surface topography. Zhao and co-workers constructed virus-like mesoporous
silica nanoparticles … Encouraged by the excellent drug delivery effect of virus-mimicking …
silica nanoparticles … Encouraged by the excellent drug delivery effect of virus-mimicking …
[HTML][HTML] Morphological and constituent viral-mimicking self-assembled nanoparticles promote cellular uptake and improve cancer therapeutic efficiency in vivo
W Zhang, Z Zhai, S Huang, Z Mao, Y Zhang, C Gao - Giant, 2020 - Elsevier
… of nano-architectures in cellular delivery. We report herein the … viral-mimicking NPs exhibit
significantly enhanced cellular … The surface topology of NPs is important in regulating cell–…
significantly enhanced cellular … The surface topology of NPs is important in regulating cell–…
Shape matters: morphologically biomimetic particles for improved drug delivery
J Wang, Q Li, J Xue, W Chen, R Zhang… - Chemical Engineering …, 2021 - Elsevier
… of virus-like particles are those mimicking the viral capsid … rough surface topography could
enable improved binding of … solution of upconversion nanoparticles and radical precursors, as …
enable improved binding of … solution of upconversion nanoparticles and radical precursors, as …