[HTML][HTML] Physalin pool from Physalis angulata L. leaves and physalin D inhibit P2X7 receptor function in vitro and acute lung injury in vivo
JCC Arruda, NC Rocha, EG Santos… - Biomedicine & …, 2021 - Elsevier
… treated these cells with P2X7 receptor antagonists or physalin extract … There were no significant
changes for the radius of the … , stylissadines A (IC 50 = 0.7 μM) and B (IC 50 = 1.8 μM), as …
changes for the radius of the … , stylissadines A (IC 50 = 0.7 μM) and B (IC 50 = 1.8 μM), as …
A Hybrid Approach Combining Shape-Based and Docking Methods to Identify Novel Potential P2X7 Antagonists from Natural Product Databases
NCS Ferreira, LG Viviani, LM Lima, AT Amaral… - Pharmaceuticals, 2024 - mdpi.com
… potential P2X7 receptor antagonists from natural products through … from natural products
[16], highlighting their importance in … into the AmP2X7 allosteric binding pocket (see Figure 3B), …
[16], highlighting their importance in … into the AmP2X7 allosteric binding pocket (see Figure 3B), …
Eugenia sulcata (Myrtaceae) Nanoemulsion Enhances the Inhibitory Activity of the Essential Oil on P2X7R and Inflammatory Response In Vivo
BQ Magalhães, FP Machado, PS Sanches, B Lima… - Pharmaceutics, 2022 - mdpi.com
… The P2X7 receptor (P2X7R) is atypical because when stimulated by a low … P2X7 receptor
antagonists, ESO, and ESON were … Stylissadines A and B, two Australian marine sponges from …
antagonists, ESO, and ESON were … Stylissadines A and B, two Australian marine sponges from …
Coral Reef: A Source Of Valueadded Compounds Beneath The Water
SB Mishra, S Singh - Immune-Boosting Nutraceuticals for Better …, 2024 - taylorfrancis.com
… However, the promising importance of coral reefs as a huge … receptor named P2X7 hence
known as P2X7 antagonists. … synthesis of Axinellamines A and B as well as the synthesis of …
known as P2X7 antagonists. … synthesis of Axinellamines A and B as well as the synthesis of …
Marine alkaloids with anti-inflammatory activity: Current knowledge and future perspectives
CRM Souza, WP Bezerra, JT Souto - Marine Drugs, 2020 - mdpi.com
… Stylissadines A (16) and B (17), two alkaloids obtained from the sponge Stylissa flabellata,
showed a specific antagonistic effect on P2X7 receptors … as one of the main products [96,97]. …
showed a specific antagonistic effect on P2X7 receptors … as one of the main products [96,97]. …
Total synthesis of (±)-N-methyldibromoisophakellin and N-methylugibohlin via net [3+ 2] cycloguanidinylations employing 2-amido-1, 3-diamino-allyl cations
… Pyrrole-aminoimidazole alkaloids (PAIs) are one of the largest natural product families isolated
… → H11) with the latter NOE absent from the oxime isomers 26a/b in conjunction with 15 N …
… → H11) with the latter NOE absent from the oxime isomers 26a/b in conjunction with 15 N …
Total Synthesis of Nagelamide W
… most complex members, stylissadines A and B, reported to … total syntheses of marine natural
products due to their highly … the key imidazoline core of the natural product. (15) Alkene 6 …
products due to their highly … the key imidazoline core of the natural product. (15) Alkene 6 …
Biomimetic approach towards alkaloid natural product synthesis and the synthesis of epicocconone analogues with near infra-red fluorescence
WL Loa-Kum-Cheung - 2022 - figshare.mq.edu.au
… natural products provides valuable information for the design of efficient routes for complex
natural products … thought to play an important role in the biosynthesis of these marine natural …
natural products … thought to play an important role in the biosynthesis of these marine natural …