… understand the nature of the autoimmune response underlying … about the role of autoantibodies
and autoreactive B cells in … by the immune system and evoke an antibody response.108 …

… infection or immunization, our immune system also produces natural antibodies (nAbs) that
… the natural antibody repertoire and the mechanisms of antibody-mediated immune regulation …

… autoantibodies mediate the clinical manifestations. Additional studies are needed to show
that the autoantibody induces pathology. … balance of the immune system processes, creating a …

… The Review specifically mentions the expansion of antibody-mediated pathology into …
antibody-mediated defence independent of T cells and an adaptive immune response 72 . …

… Another mechanism to consider is secondary to the presence of natural autoantibodies, …
effect on the immune system by inhibiting B cell proliferation and antibody production and also …

… the immune response, impacting the maintenance of immune … immunity and accelerating
chronic disease pathogenesis (eg… the production of natural non-pathogenic autoantibodies [151]…

… for the maternal immune system which is confronted with … of natural killer cells (NK) and
other cells of the innate immune … of autoantibodies with their target antigen is involved in the …

… The immune system serves as a physiological sensory and … The issue of natural autoantibodies
and physiological … of systemic autoimmune rheumatic pathology, represents a biomarker …

… the need to differentiate these autoantibodies from natural autoantibodies is emphasized. In
… adaptive immune systems are recruited in SSc pathogenesis and adaptive humoral immune …

… at physiological concentrations the human immune system … involved in the pathogenesis of
immune-mediated diseases and … the same epitopes targeted by human auto-antibodies [240]. …