Natural killer cell therapy targeting cancer stem cells: old wine in a new bottle
F Guo, Y Zhang, L Bai, J Cui - Cancer Letters, 2023 - Elsevier
… conversion between differentiated tumor cells and CSCs under … cancer, estrogen receptor-α
positive breast cancer stem-like … increased ability to target solid tumor stem-like cells both in …
positive breast cancer stem-like … increased ability to target solid tumor stem-like cells both in …
[HTML][HTML] Natural killer cells: diverse functions in tumor immunity and defects in pre-neoplastic and neoplastic stages of tumorigenesis
… /undifferentiated tumors via lysis, and secreted or membrane-… of NK cells in selection and
differentiation of stem-like tumors … targeting cancer stem-like/undifferentiated tumors, NK cells …
differentiation of stem-like tumors … targeting cancer stem-like/undifferentiated tumors, NK cells …
[HTML][HTML] … MICA/B is mediated against differentiated oral and pancreatic and not stem-like/poorly differentiated tumors by the NK cells; loss in cancer patients due to …
… Natural Killer cells are known to eliminate tumors directly or via … of tumor killing. In this
report we provide evidence that NK cells mediate killing of both stem-like/poorly differentiated …
report we provide evidence that NK cells mediate killing of both stem-like/poorly differentiated …
Multifaceted nature of natural killer cells: Potential mode of interaction and shaping of stem cells
… , as they were only able to kill certain tumor cells, but not those highly susceptible to T cell …
they preferentially targeted cancer stem-like cells (CSCs)/poorly-differentiated tumor cells that …
they preferentially targeted cancer stem-like cells (CSCs)/poorly-differentiated tumor cells that …
[HTML][HTML] Exploring the Potential of Natural Killer Cell-Based Immunotherapy in Targeting High-Grade Serous Ovarian Carcinomas
… cancers (HGSOCs) likely consist of poorly differentiated stem-like cells (PDSLCs) and
differentiated tumor cells. … will refer to these cells as poorly differentiated stem-like cells (PD-SLCs) …
differentiated tumor cells. … will refer to these cells as poorly differentiated stem-like cells (PD-SLCs) …
[HTML][HTML] Natural killer cells efficiently target multiple myeloma clonogenic tumor cells
A Leivas, RM Risueño, A Guzmán… - Cancer Immunology …, 2021 - Springer
… of immune cells, such as T cells and natural killer (NK) cells, is … cell capacity to kill transformed
or infected cells and tumor … of stem cell differentiation and stem cell maintenance were …
or infected cells and tumor … of stem cell differentiation and stem cell maintenance were …
Role of Natural Killer Cells as Cell-Based Immunotherapy in Oral Tumor Eradication and Differentiation Both In Vivo and In Vitro
… oral tumors: oral squamous carcinoma stem-like cells (OSCSCs) and oral squamous …
Natural killer cells target and differentiate cancer stemlike cells/undifferentiated tumors: Strategies …
Natural killer cells target and differentiate cancer stemlike cells/undifferentiated tumors: Strategies …
[HTML][HTML] EpCAM-high liver cancer stem cells resist natural killer cell–mediated cytotoxicity by upregulating CEACAM1
… were shown to be major immune effectors with the ability to target and shape several
poorly differentiated tumors, such as oral, glioblastoma, pancreatic, and melanoma …
poorly differentiated tumors, such as oral, glioblastoma, pancreatic, and melanoma …
Advances in natural killer cell therapies for breast cancer
SZF Kiaei, A Nouralishahi… - … and Cell Biology, 2023 - Wiley Online Library
… Natural killer (NK) cells are an essential component of innate immunity and are critical in
destroying tumor cells without … HLA alleles determine differences in human natural killer cell …
destroying tumor cells without … HLA alleles determine differences in human natural killer cell …
Novel strategies to expand supercharged NK cells with augmented capacity to withstand inactivation by tumors
… Natural killer (NK) cells are the main immune effectors with … /undifferentiated or poorly
differentiated tumors via lysis, and … role in targeting cancer stem-like/undifferentiated tumors, and a …
differentiated tumors via lysis, and … role in targeting cancer stem-like/undifferentiated tumors, and a …