Natural and synthetic naphthoquinones as potential anti-infective agents

E Ortiz-Pérez, G Rivera, CO Salas… - … Medicinal Chemistry, 2021 - ingentaconnect.com
… than natural compounds. Conclusion: In this review, natural and synthetic naphthoquinones
showed … Therefore, naphthoquinones are important molecules in the development of new …

1, 4-Naphthoquinones: some biological properties and application

D Aminin, S Polonik - Chemical and Pharmaceutical Bulletin, 2020 - jstage.jst.go.jp
… 1,4-Naphthoquinone (1) or para-naphthoquinone is a natural organic compound derived
from naphthalene. Oxidation of two atoms of the benzene ring in the α-position of the …

Naphthoquinones and derivatives for chemotherapy: perspectives and limitations of their anti-trypanosomatids activities

L Dantas-Pereira, EF Cunha-Junior… - … Pharmaceutical …, 2021 - ingentaconnect.com
… In folk medicine, natural naphthoquinones have been employed for the treatment of a great
… Multidisciplinary initiatives embracing medicinal chemistry, bioinformatics, biochemistry, …

Natural naphthoquinones and their derivatives as potential drug molecules against trypanosome parasites

R Rani, K Sethi, S Kumar, RS Varma… - Chemical Biology & …, 2022 - Wiley Online Library
… 1.1 Naphthoquinones as privileged molecules Naphthoquinones are considered as fortunate
structures in the field of medicinal chemistry owing to their different biological potentials …

Journey on naphthoquinone and anthraquinone derivatives: new insights in Alzheimer's disease

M Campora, V Francesconi, S Schenone, B Tasso… - Pharmaceuticals, 2021 - mdpi.com
… continue to inspire the medicinal chemist as molecular targets for the … of recent advancements
on naphthoquinone (NQ) and … NQs are colored chemical compounds that exist in nature as …

Naphthoquinone derivatives isolated from plants: recent advances in biological activity

ES Ahmadi, A Tajbakhsh, M Iranshahy… - … Medicinal Chemistry, 2020 - ingentaconnect.com
… Lapachol [7] and the structurally related compound lapachone [8] are two natural prenylated
NQs with special significance in cancer treatment. β-Lapachone is in phase II clinical trials …

Naphthoquinones and their derivatives: emerging trends in combating microbial pathogens

NS Mone, SA Bhagwat, D Sharma, M Chaskar… - Coatings, 2021 - mdpi.com
… The unique structural, biological, and functional properties of naphthoquinones (NQs), …
from a medicinal chemistry perspective [18]. NQs are widely distributed as natural pigments in …

1, 4‐Naphthoquinone: A Privileged Structural Framework in Drug Discovery

UA Dar, M Kamal, SA Shah - Chemistry of Biologically Potent …, 2021 - Wiley Online Library
… explored in drug and medicinal chemistry. Quinone plays vital role in electron transport in …
In most of cases, pharmacological activity of naphthoquinone has been influenced by redox …

Naphthoquinones and derivatives as potential anticancer agents: An updated review

MM Rahman, MR Islam, S Akash, S Shohag… - Chemico-Biological …, 2022 - Elsevier
Naphthoquinones are a type of quinone that is found in nature and has vital biological roles.
… In medicinal chemistry, naphthoquinones—a name introduced by Evans et al. to describe …

Naphthoquinones in the Treatment of Cancer

SP Kumar, P Mallya, V Jain - Journal of Pharmaceutical …, 2020 - search.proquest.com
role in bio-oxidative processes and chemical defence. Examples of natural naphthoquinones
… Journal of medicinal chemistry, 58(21), pp.8491-8502. 19. Yu, H., Pardoll, D. and Jove, R., …