Antimicrobial and cytotoxic naphthoquinones from microbial origin: an updated review

ME Kashi, M Ghorbani, H Badibostan… - … Medicinal Chemistry, 2024 - ingentaconnect.com
… to find out their specialized products with desired medicinal activities. Various groups of …
Quinones are cyclic organic compounds that naturally occur in bacteria, fungi, viruses, and …

An Update on the Synthesis and Applications of Bis (Naphthoquinones): An Important Class of Molecules against Infectious Diseases and other Conditions

L da SM Forezi, AS de Souza, CGS Lima… - … Medicinal Chemistry, 2021 - ingentaconnect.com
… Many other naphthoquinones occur in nature as secondary metabolites in fauna and flora, …
1), for instance, is a natural naphthoquinone that has a long history of use in folk medicine, …

Description of Some Methodologies for the Synthesis of 1, 4-Naphthoquinone Derivatives and Examples of their Biological Activity: A Review

SE Loredo-Carrillo, E Leyva… - … Organic Chemistry, 2024 - ingentaconnect.com
… The synthetic modification to natural compounds such as naphthoquinonesmedicinal
chemistry, indole is a particularly important structure since it binds to multiple receptors with high

Naphthoquinone Derivatives Targeting Melanoma

JA Nunes, AF da Silva Nunes… - … Medicinal Chemistry, 2023 - ingentaconnect.com
relevance for medicinal chemistry, with emphasis on … Therefore, in this review, the natural
naphthoquinones studied … the research involving such natural compounds for the treatment of …

Mechanism of Action and Implication of Naphthoquinone as Potent Anti-trypanosomal Drugs

R Rani, K Sethi, S Gupta, RS Varma… - … in Medicinal Chemistry, 2022 - ingentaconnect.com
… Abstract: Naphthoquinone is a heterocyclic moiety whose naturalNaphthoquinone agents
have dynamic pharmacophores and privileged sub-structures in the chemistry of medicine. …

p-Benzoquinone as a privileged scaffold of pharmacological significance: A Review

P Silakari, P Piplani - Mini reviews in medicinal chemistry, 2020 - ingentaconnect.com
natural occurrences of p-benzoquinone derivatives with different pharmacological significance
… of the most interesting nuclei playing a vital role in both chemical and life sciences. This …

[HTML][HTML] Unlocking the potential of 1, 4-naphthoquinones: A comprehensive review of their anticancer properties

E Angulo-Elizari, A Henriquez-Figuereo… - … of Medicinal Chemistry, 2024 - Elsevier
… 4-naphthoquinone as a scaffold in synthetic or natural products … 1,4-naphthoquinone and its
natural and synthetic derivatives … The work describes the main natural naphthoquinones with …

In silico, in vitro and in vivo evaluation of natural Bignoniaceous naphthoquinones in comparison with atovaquone targeting the selection of potential antimalarial …

MFA do Nascimento, TF Borgati, LCR de Souza… - Toxicology and Applied …, 2020 - Elsevier
… to evaluate the antimalarial potential of the natural naphthoquinones lapachol, α- and β-…
The in silico ADMET prediction of these naphthoquinones by the PreADMET program was …

Naphthoquinone-based hydrazone hybrids: synthesis and potent activity against cancer cell lines

DG Guimaraes, A de Assis Gonsalves… - … Chemistry, 2021 - ingentaconnect.com
… Abstract: Background: Natural naphthoquinones have shown diversified biological activities
including antibacterial, antifungal, antimalarial, and cytotoxic activities. However, they are …

Redox ticklers and beyond: Naphthoquinone repository in the spotlight against inflammation and associated maladies

N Kapoor, P Kandwal, G Sharma, L Gambhir - Pharmacological Research, 2021 - Elsevier
… owing to their prooxidants nature. Owing to the ability of naphthoquinones and its derivatives
to perturb … The present review highlights the potential of 1,4-naphthoquinone and its natural