Good pyridine hunting: a biomimic compound, a modifier and a unique pharmacophore in agrochemicals

VV Zakharychev, AV Kuzenkov… - Chemistry of Heterocyclic …, 2020 - Springer
products have been described based on the pyridine scaffold making it the most commercially
successful heterocycle in the synthesis of plant protection chemicals … in combination with …

[HTML][HTML] Natural compounds as guides for the discovery of drugs targeting G-protein-coupled receptors

J Serrano-Marín, I Reyes-Resina, E Martínez-Pinilla… - Molecules, 2020 - mdpi.com
… This review focuses on natural products (excluding peptides) that target GPCRs. Natural
Individually or in combination, they are consumed worldwide to increase alertness and …

[图书][B] Asymmetric synthesis of natural products

AMP Koskinen - 2022 - books.google.com
… the hype for combinatorial chemistry faded as … hunters to envenomate their poison darts.
The Columbian Golden poison frog Phyllobates terribilis is perhaps the most poisonous land

[HTML][HTML] Modern approaches in the discovery and development of plant-based natural products and their analogues as potential therapeutic agents

A Najmi, SA Javed, M Al Bratty, HA Alhazmi - Molecules, 2022 - mdpi.com
… mentioned that 23 natural products with diverse chemical structures found a place in the …
can also be prepared by using synthetic chemistry and combinatorial chemistry. Among the …

[HTML][HTML] Natural products in cancer therapy: Past, present and future

M Huang, JJ Lu, J Ding - Natural products and bioprospecting, 2021 - Springer
… research has been drawn to into molecularly targeted drug hunting. These efforts yielded
a large … Moreover, the combination therapy strategy is particularly meaningful to bioactive …

Medicinal chemistry of isocyanides

A Massarotti, F Brunelli, S Aprile, M Giustiniano… - Chemical …, 2021 - ACS Publications
… status of an important reactive functional group in organic and combinatorial chemistry, and
today it is widely employed in both photocatalysis and transition metal chemistry. (5−7) It is …

Natural product-based crop protection compounds─ origins and future prospects

TC Sparks, JM Sparks, SO Duke - … Agricultural and Food Chemistry, 2023 - ACS Publications
Natural products (NPs) have long been an key area of interest in the discovery of new crop
protection AIs, (5,18−24) representing one of the most common approaches employed by …

Dearomative logic in natural product total synthesis

CJ Huck, YD Boyko, D Sarlah - Natural product reports, 2022 - pubs.rsc.org
… , with a focus on natural product total synthesis and retrosynthetic analysis. Disconnection
… to nature's use of dearomatization in the biosynthesis of various classes of natural products. …

Chemists: AI is here; unite to get the benefits

EJ Griffen, AG Dossetter, AG Leach - … of Medicinal Chemistry, 2020 - ACS Publications
chemistry and the drug hunting aspects of computational chemistry the combination of … ,
high throughput screening, combinatorial chemistry, and automated chemistry. It would be easy …

[HTML][HTML] Swarm hunting and cluster ejections in chemically communicating active mixtures

J Grauer, H Löwen, A Be'er, B Liebchen - Scientific Reports, 2020 - nature.com
huntinghunting swarms in fact occur generically if the chemical interactions are strong
enough and have opposite sign. However, if the response of hunters and prey to the chemicals