… kidneys with an antibody for SIX2 to detect nephron progenitors in the cap mesenchyme at
E14.5, … Our data show that FGF8 prevents nephron progenitor apoptosis and maintains Lhx1 …

… In addition, complementing the directed differentiation from hPSCs, our group and others
have developed culture conditions to expand primary mouse and human nephron progenitor …

… We now aim to study Tcf21 in nephron progenitor cells (NPC). During nephrogenesis,
WNT9b signals to NPC through the canonical Wnt/β-catenin pathway, which promotes both self-…

… Renal progenitor cells self-organize into nephrons by … , high concentration of human nephron
progenitor cells (NPCs) … chance efficiently for generating chimeric nephrons. Therefore, we …

… has been dedicated towards the isolation of nephron progenitor cells (NPCs) from both … the
generation of renal progenitor cells including intermediate mesoderm progenitors (IM), NPCs, …

… We will now introduce the generation of nephron progenitors and UBs from mouse ESCs
or human iPSCs, and provide an overview on the current status and futuristic goals of kidney …

… of nephron progenitor organization and cell morphology in the earliest stages of nephron …
to a poorly polarized nephron epithelium and likely poor nephron function. These studies …

… Bmp7 is expressed both by nephron progenitor cells and the … new nephrons. Here, we
show that, in mice, Bmp7 expressed by progenitor cells has a major role in determining nephron …

… Each of these kidney structures originates from populations of mesodermally derived renal
progenitors. The zebrafish pronephros is extremely simple, being comprised of two nephrons …

… We show efficient cryopreservation of differentiating kidney progenitors which alleviates the
need for continuous hiPSCs culture and differentiation, and gives rise to an accessible stock …