Evaluating the role of Neuregulin-1β1 in neuroprotection after spinal cord injury

N Shahsavani - 2021 - mspace.lib.umanitoba.ca
… been implicated in modulation of neuroinflammation through inhibition of NF-κB activity and
… -relevant model of compressive/contusive SCI in rats and an in vitro model of glutamate …

[HTML][HTML] Microglia remodelling and neuroinflammation parallel neuronal hyperactivation following acute organophosphate poisoning

J Somkhit, C Yanicostas… - International Journal of …, 2022 - mdpi.com
… poisoned humans and preclinical models, including AChE inhibition, neuronal epileptiform
… and animal models [10]. Specifically, it has been clearly established that neuroinflammation

[HTML][HTML] Neuroinflammation as a therapeutic target for mitigating the long-term consequences of acute organophosphate intoxication

PM Andrew, PJ Lein - Frontiers in pharmacology, 2021 - frontiersin.org
animal models (see below), there are data suggesting a similar neuroinflammatory response
… These observations indicate that timing of pharmacologic inhibition of neuroinflammation is …

[图书][B] Investigating Gene Expression Effects of Neuregulin-1 (NRG-1) and its Influence on Response to Inflammatory Stimulation with LPS in Microglial Cells In Vitro

CJ Augello - 2022 - search.proquest.com
… over neuroinflammation with respect to classical pro-and anti-inflammatory states within an
in vitro model of … In a rat model of compressive SCI, immediate addition of exogenous NRG-1 …

Neuregulin-1 beta 1 is implicated in pathogenesis of multiple sclerosis

H Kataria, CG Hart, A Alizadeh, M Cossoy, DK Kaushik… - Brain, 2021 - academic.oup.com
… To unravel the underlying mechanisms by which Nrg-1β1 inhibits leucocyte infiltration into …
cells reflects their functional impact on the neuroinflammatory response in EAE. Thus, we also …

[HTML][HTML] A rat model of organophosphate-induced status epilepticus and the beneficial effects of EP2 receptor inhibition

A Rojas, T Ganesh, W Wang, J Wang… - Neurobiology of …, 2020 - Elsevier
rat model of status epilepticus (SE) induced by diisopropyl fluorophosphate (DFP), and the
beneficial outcomes of transient inhibition … the level of neuroinflammation, neurodegeneration …

[PDF][PDF] Neuroinflammation as a therapeutic target for mitigating the long-term consequences of acute organophosphate intoxication. Front Pharmacol 12: 674325

PM Andrew, PJ Lein - Frontiers in Pharmacology| www. frontiersin …, 2021 - researchgate.net
… of neuroinflammatory responses after acute OP intoxication, drawing parallels to other …
Neuregulin-1 Inhibits Neuroinflammatory Responses in a Rat Model of Organophosphate-Nerve

[HTML][HTML] Neuregulin1: An underlying protective force of cardiac dysfunction in sepsis

W Kang, Y Cheng, X Wang, F Zhou… - Molecular …, 2020 - spandidos-publications.com
rats were studied using animal models. … rats, and ErbB4 antagonists can inhibit this effect
(15,81). Other studies have demonstrated that NRG-1 may improve symptoms in animal models

[HTML][HTML] … exposure to an obesogenic diet during adolescence elicits anxiety-related behavior and neuroinflammation: modulatory effects of exogenous neuregulin-1

JD Vega-Torres, P Ontiveros-Angel, E Terrones… - Translational …, 2022 - nature.com
… to models of neuroinflammation, including cerebral malaria [36], nerve agent intoxication [37],
and ischemia [38]. Studies demonstrate that ErbB4 inhibition … function in our rat model. We …

[HTML][HTML] Persistent behavior deficits, neuroinflammation, and oxidative stress in a rat model of acute organophosphate intoxication

M Guignet, K Dhakal, BM Flannery, BA Hobson… - Neurobiology of …, 2020 - Elsevier
… These acute effects include rapid and profound inhibition of … , and robust neuroinflammatory
responses, increased expression … as extensively characterized in the rat model of acute DFP …