Extracellular vesicle membrane-associated proteins: emerging roles in tumor angiogenesis and anti-angiogenesis therapy resistance

SY Ko, H Naora - International journal of molecular sciences, 2020 - mdpi.com
… on the vesicular surface. This review discusses and integrates emerging insights into the
diverse … proteins in tumor angiogenesis, and the clinical significance of these proteins in anti-…

Extracellular vesicles are key regulators of tumor neovasculature

N Kuriyama, Y Yoshioka, S Kikuchi… - Frontiers in Cell and …, 2020 - frontiersin.org
… play multiple roles, contributing to tumor angiogenesis, … tumor angiogenesis through the
phenotype switching of various cells into cancer-associated fibroblasts, the activation of tumor

Platelets extracellular vesicles as regulators of cancer progression—an updated perspective

M Żmigrodzka, O Witkowska-Piłaszewicz… - International journal of …, 2020 - mdpi.com
… In addition, EVs are also secreted by cancer cells known as tumor-derived extracellular
vesicles (TEVs) [4,12]. In both healthy subjects and those with a variety of pathologies, peripheral …

Role of extracellular vesicles in tumour microenvironment

SC Tao, SC Guo - Cell Communication and Signaling, 2020 - Springer
… In recent years, it has been demonstrated that extracellular vesicles (EVs) can be released
by almost all cell types, and detected in most body fluids. In the tumour microenvironment (…

Message in a bottle: Endothelial cell regulation by extracellular vesicles

C Palazzo, A D'Alessio, L Tamagnone - Cancers, 2022 - mdpi.com
… that cancer cell-derived EVs can control the functions of ECs … of their roles in tumor
angiogenesis and cancer progression. … the roles of exosomes in EC regulation within the tumor

[HTML][HTML] The role of extracellular vesicles in non-small-cell lung cancer, the unknowns, and how new approach methodologies can support new knowledge generation …

S Mullen, D Movia - European Journal of Pharmaceutical Sciences, 2023 - Elsevier
Extracellular vesicles (EVs) are nanosized particles … knowledge demonstrates that EVs
also play critical roles in many aspects of the progression of Non-Small-Cell Lung Cancer

Small extracellular vesicles: a novel avenue for cancer management

Y Gao, Y Qin, C Wan, Y Sun, J Meng, J Huang… - Frontiers in …, 2021 - frontiersin.org
… models, it can be adapted for anti-angiogenesis therapy in cancer models, given the role
of integrin αvβ3 in promoting tumor angiogenesis (151). Modified nucleic acids could also be …

The roles of small extracellular vesicles in cancer and immune regulation and translational potential in cancer therapy

K Qian, W Fu, T Li, J Zhao, C Lei, S Hu - … of Experimental & Clinical Cancer …, 2022 - Springer
… among multiple cells in the tumour environment. Small extracellular vesicles (sEVs) are
defined as EVs range in diameter from approximately 50 to 150 nm. Tumour-derived sEVs (…

Tumor-derived extracellular vesicles regulate cancer progression in the tumor microenvironment

Q Bao, Q Huang, Y Chen, Q Wang, R Sang… - Frontiers in molecular …, 2022 - frontiersin.org
Extracellular vesicles (EVs) are nanosized particles released by numerous kinds of cells,
which are now increasingly considered as essential vehicles of cell-to-cell communication and …

The role of the metabolite cargo of extracellular vesicles in tumor progression

M Harmati, M Bukva, T Böröczky, K Buzás… - Cancer and Metastasis …, 2021 - Springer
insight into EV biology and the technical aspects of EV studies. We also describe the current
knowledge on the functional role of the EV-transferred metabolites in tumor progression. …