[HTML][HTML] Next generation sequencing for gene fusion analysis in lung cancer: a literature review

R Bruno, G Fontanini - Diagnostics, 2020 - mdpi.com
techniques can be used, from fluorescence in situ hybridization and immunohistochemistry
to next generation sequencing … fusion testing presents more technical challenges than other …

… of liquid-based to tissue-based biopsy analysis by targeted next generation sequencing in advanced non-small cell lung cancer: a comprehensive systematic review

SM Esagian, GΙ Grigoriadou, IP Nikas, V Boikou… - Journal of cancer …, 2020 - Springer
… In conclusion, most advanced NSCLC patients are unresectable and are diagnosed with
small biopsies or cytology, both of which may have insufficient DNA for molecular analysis. This …

[HTML][HTML] Application of next generation sequencing in laboratory medicine

Y Zhong, F Xu, J Wu, J Schubert… - Annals of laboratory …, 2021 - ncbi.nlm.nih.gov
… NGS technologies and their clinical application in diagnosis, … for all advanced-stage lung
cancers; if these are negative, … The use of NGS technology in lung cancer tests has proven …

[HTML][HTML] Next-generation sequencing technology: current trends and advancements

H Satam, K Joshi, U Mangrolia, S Waghoo, G Zaidi… - Biology, 2023 - mdpi.com
… Whereas long-read sequencing works on sequence detection either by synthesis or by …
in cancer pathogenesis and build on the cancer genomics database. Lung cancer biomarkers …

[HTML][HTML] When should we order a next generation sequencing test in a patient with cancer?

R Colomer, R Mondejar, N Romero-Laorden… - …, 2020 - thelancet.com
… a next-generation sequencing-based in vitro diagnostic test that uses RNA isolated from
formalin-fixed paraffin embedded (FFPE) tumor … in non-small-cell lung cancer: results of a 2-year …

[HTML][HTML] Recommendations for the use of next-generation sequencing (NGS) for patients with metastatic cancers: a report from the ESMO Precision Medicine Working …

F Mosele, J Remon, J Mateo, CB Westphalen… - Annals of …, 2020 - Elsevier
… they are often driving diagnostic innovation at times when … sequencing in daily practice
is weak.18, 19, 20, 21 We identified two economic studies in non-small-cell lung cancer (NSCLC). …

Utility of incorporating next-generation sequencing (NGS) in an Asian non-small cell lung cancer (NSCLC) population: Incremental yield of actionable alterations and …

AC Tan, GGY Lai, G San Tan, SY Poon, B Doble… - Lung Cancer, 2020 - Elsevier
… We sought to compare the performance of targeted next-generation sequencing (NGS) …
lung cancer is increasing and Asia accounts for over half of new lung cancer cases diagnosed

[HTML][HTML] Genetic markers in lung cancer diagnosis: a review

K Wadowska, I Bil-Lula, Ł Trembecki… - International journal of …, 2020 - mdpi.com
… profiles have the greatest diagnostic potential value in lung cancer diagnosis, but their …
and next-generation sequencing (NGS) as a pre-step that provides the sequencing of the …

[HTML][HTML] Detection of gene fusions using targeted next-generation sequencing: a comparative evaluation

C Heydt, CB Wölwer, O Velazquez Camacho… - BMC medical …, 2021 - Springer
… Although only 10 ng of RNA were needed, the Oncomine Focus Assay (Thermo Fisher
Scientific) was the least adequate assay for our purposes, as seven targetable lung cancer fusion …

[HTML][HTML] Current and future development in lung cancer diagnosis

R Nooreldeen, H Bach - International journal of molecular sciences, 2021 - mdpi.com
… Targets), and Foundation One CDx are FDA-approved next-generation sequencing (NGS)-based
platforms for molecular testing. Broader NGS-based assays can evaluate emerging …