Spectrum of driver mutations and clinical impact of circulating tumor DNA analysis in non–small cell lung cancer: Analysis of over 8000 cases

PC Mack, KC Banks, CR Espenschied, RA Burich… - Cancer, 2020 - Wiley Online Library
… available digital next-generation sequencing platform in a … .1, 3 As new generations of
targeted agents—characterized by … from all individuals with a diagnosis of advanced (defined on …

… burden and immunological, genomic, and clinicopathological factors as biomarkers for checkpoint inhibitor treatment of patients with non-small-cell lung cancer

Y Ozaki, S Muto, H Takagi, M Watanabe… - Cancer Immunology …, 2020 - Springer
Lung cancer recurrence was seen in 22 patients (24.2%) except 1 patient with stage IV
adenocarcinoma diagnosed … Whole-exome sequencing by next-generation sequencing was …

Diagnostic performance of metagenomic next-generation sequencing for Pneumocystis jirovecii pneumonia

X Li, Z Li, J Ye, W Ye - BMC Infectious Diseases, 2023 - Springer
… Forest plot of sensitivity and specificity for metagenomic next-generation sequencing in
diagnosis of immunocompromised patients with Pneumocystis jirovecii pneumonia. The pooled …

Blood-derived lncRNAs as biomarkers for cancer diagnosis: the Good, the Bad and the Beauty

C Badowski, B He, LX Garmire - NPJ precision oncology, 2022 - nature.com
… subjects by RT-qPCR or Next Generation Sequencing. … blood-based biomarker for lung
cancer diagnosis (Table 1). One … -1 in lung cancer patients and the levels of this lncRNA in lung

Practical considerations for the use of circulating tumor DNA in the treatment of patients with cancer: a narrative review

MG Krebs, U Malapelle, F André, L Paz-Ares… - JAMA …, 2022 - jamanetwork.com
next-generation sequencing (eg, capture-based profiling, whole exome, or genome sequencing).
… are treatment-naive and newly diagnosed with lung cancer, if histologic specimens are …

Detection and characterization of lung cancer using cell-free DNA fragmentomes

D Mathios, JS Johansen, S Cristiano, JE Medina… - Nature …, 2021 - nature.com
… The concentration and quality of cfDNA were assessed using the Bioanalyzer 2100 (Agilent
Technologies). Next-generation sequencing (NGS) cfDNA libraries were prepared for WGS …

Plasma level of circular RNA hsa_circ_0000190 correlates with tumor progression and poor treatment response in advanced lung cancers

YH Luo, YP Yang, CS Chien, AA Yarmishyn, AA Ishola… - Cancers, 2020 - mdpi.com
… for cancer detection, diagnosis, and prediction of treatment efficacy in advanced LC. … next
generation sequencing (NGS) of the transcriptomes of two distinct lung adenocarcinoma cell …

Next-generation sequencing (NGS) in COVID-19: a tool for SARS-CoV-2 diagnosis, monitoring new strains and phylodynamic modeling in molecular epidemiology

G John, NS Sahajpal, AK Mondal, S Ananth… - Current issues in …, 2021 - mdpi.com
… -19 diagnosis and explores next-generation sequencing (NGS) technology for the detection
of … facing the application of NGS technologies for the diagnosis, surveillance, and study of …

Deep learning in cancer pathology: a new generation of clinical biomarkers

A Echle, NT Rindtorff, TJ Brinker, T Luedde… - … journal of cancer, 2021 - nature.com
… for non-small-cell lung cancer (NSCLC) is influenced by a … DL systems for prostate cancer
detection and grading with … reaction (PCR) or next-generation sequencing (NGS), performed in …

Liquid biopsy for therapy monitoring in early-stage non-small cell lung cancer

M Nagasaka, MH Uddin, MN Al-Hallak, S Rahman… - Molecular Cancer, 2021 - Springer
… the necessity of highly sensitive detection technologies. Besides quantitative PCR (qPCR)
and next-generation sequencing (NGS), recently developed techniques, such as digital PCR (…