Inhibition of IL1β by canakinumab may be effective against diverse molecular subtypes of lung cancer: an exploratory analysis of the CANTOS trial

CC Wong, J Baum, A Silvestro, MT Beste… - Cancer research, 2020 - AACR
… Box plots of time to lung cancer diagnosis for patients with lung cancer from CANTOS with
baseline … In fact, the new generation of ctDNA assays tend to prioritize on different aspects of …

cfDNA methylome profiling for detection and subtyping of small cell lung cancers

F Chemi, SP Pearce, A Clipson, SM Hill, AM Conway… - Nature cancer, 2022 - nature.com
… To evaluate SCLC genome-wide DNA methylation patterns, we employed a bisulfite-free,
enrichment-based next-generation sequencing (NGS) approach that incorporated an in-house …

Assessment of the clinical utility of plasma metagenomic next-generation sequencing in a pediatric hospital population

RA Lee, F Al Dhaheri, NR Pollock… - Journal of clinical …, 2020 - Am Soc Microbiol
… In the absence of a reference gold standard for this novel technology, we report positive
percent agreement (PPA; agreement between mNGS test and infection diagnosis determined by …

Longitudinal undetectable molecular residual disease defines potentially cured population in localized non–small cell lung cancer

JT Zhang, SY Liu, W Gao, SYM Liu, HH Yan, L Ji… - Cancer Discovery, 2022 - AACR
… The detection of ctDNA-MRD is based on capture-based next-generation sequencing (NGS) …
A customized panel was designed to cover frequently mutated genes in lung cancer (…

Changing technologies of RNA sequencing and their applications in clinical oncology

Y Wang, M Mashock, Z Tong, X Mu, H Chen… - Frontiers in …, 2020 - frontiersin.org
diagnosis is the Lung NGS Fusion Profile offered by NEO Genomics. This RNA-based
next-generation sequencing … Neuroblastoma (16), and Lung Adenocarcinoma (17), and predictive …

EGFR exon 20 insertion mutations in Chinese advanced non-small cell lung cancer patients: molecular heterogeneity and treatment outcome from nationwide real …

G Yang, J Li, H Xu, Y Yang, L Yang, F Xu, B Xia… - Lung Cancer, 2020 - Elsevier
Lung cancer remains the leading cause of cancer-related mortality in the … cases of newly
diagnosed lung cancer and 610,200 lung cancer related deaths in … Next generation sequencing

FGFR fusions in cancer: from diagnostic approaches to therapeutic intervention

A De Luca, R Esposito Abate, AM Rachiglio… - International journal of …, 2020 - mdpi.com
… Deregulated FGFR signaling is observed in various tumor … in 4853 tumor samples by
next-generation sequencing (NGS), … tumor types, including glioma, lung cancer, bladder cancer, …

[HTML][HTML] Oncogenic driver mutations in non-small cell lung cancer: Past, present and future

M Chevallier, M Borgeaud, A Addeo… - World Journal of …, 2021 - ncbi.nlm.nih.gov
… cell lung cancer (NSCLC). Over the years, the adoption of next generation sequencing has
… The majority of NSCLC patients display advanced disease when diagnosed and thus have …

Lung cancer in People's Republic of China

S Gao, N Li, S Wang, F Zhang, W Wei, N Li, N Bi… - Journal of Thoracic …, 2020 - jto.org
Diagnosis There are many types of imaging that can be used for diagnosing lung cancer.
The most important technology for the diagnosis of lung cancer is high-resolution computed …

Biomarker testing in non-small cell lung cancer in routine care: Analysis of the first 3,717 patients in the German prospective, observational, nation-wide CRISP …

F Griesinger, W Eberhardt, A Nusch, M Reiser… - Lung Cancer, 2021 - Elsevier
Lung cancer belongs to the three most frequently diagnosed cancers in Germany and …
separately within the context of diagnosis of lung cancer in hospitals or specialized centers [31]. …