[HTML][HTML] The specificity of endogenous fatty acid nitration: only conjugated substrates support the in vivo formation of nitro-fatty acids

N Colussi, F Chang, FJ Schopfer - Redox Biochemistry and Chemistry, 2024 - Elsevier
… in 2003, endogenous fatty acid nitration and subsequent NO 2 -FA formation remains an
ongoing … This review will discuss the chemical characteristics of fatty acid nitration, including the …

[HTML][HTML] Electrophilic characteristics and aqueous behavior of fatty acid nitroalkenes

V Grippo, M Mojovic, A Pavicevic, M Kabelac… - Redox biology, 2021 - Elsevier
… -formed NO 2 -FA or a combination of precursor fatty acids and sources of the organic nitrates
required for fatty acid nitration … in characterizing the biophysical and biochemical properties

The nitration of proteins, lipids and DNA by peroxynitrite derivatives-chemistry involved and biological relevance

JM Pérez de la Lastra, CA Juan, FJ Plou… - Stresses, 2022 - mdpi.com
… , the exact process by which fatty acids are nitrated in vivo is unclear as yet [47]. However,
nitrated unsaturated fatty acids have chemically electrophilic characteristics that allow them to …

[HTML][HTML] Tomato pomace-derived nitrated fatty acids: Synthesis and antiplatelet activity

L Rodríguez, F Lagos, M Mastrogiovanni… - Biomedicine & …, 2024 - Elsevier
fatty acids found in tomato pomace undergo nitration during digestion. Our hypothesis aims
to explore the formation of nitrated fatty acids (… Chemical characterization of tomato pomace …

[HTML][HTML] Endogenous generation of nitro-fatty acid hybrids having dual nitrate ester (RONO2) and nitroalkene (RNO2) substituents

M Fazzari, SR Woodcock, P Rowart, K Ricart… - Redox Biology, 2021 - Elsevier
… disorders, have not been detected biologically. We characterize in rat stomach unsaturated
fatty acid nitration reactions that proceed by generation of nitro-nitrate intermediates (NO 2 –…

Nitro-fatty acids as activators of hSIRT6 deacetylase activity

M Carreño, M Bresque, MR Machado, L Santos… - … of Biological Chemistry, 2020 - ASBMB
acid promoted H3K9 deacetylation, whereas oleic acid had no effect. Altogether, our results
show that nitrated fatty acids … should be considered as a molecular target for in vivo actions …

Comparative studies on the fatty acid profile and volatile compounds of fallow deer and beef fermented sausages without nitrite produced with the addition of acid …

M Karwowska, AD Kononiuk, P Borrajo, JM Lorenzo - Applied Sciences, 2021 - mdpi.com
… are formed and contribute to the unique flavor of cured meat. To the best of our knowledge,
few studies have examined the effect of nitrate/… formation in dry sausages with reduced nitrate/…

[HTML][HTML] How do nitrated lipids affect the properties of phospholipid membranes?

MC Oliveira, M Yusupov, A Bogaerts… - Archives of Biochemistry …, 2020 - Elsevier
… studies also revealed that nitrated fatty acids alter lipid organization by cluster formation
at the membrane-water interface [12]. Moreover, nitrated phospholipids were detected in the …

Mass spectrometry-based study defines the human urine nitrolipidome

SR Salvatore, P Rowart, FJ Schopfer - Free Radical Biology and Medicine, 2021 - Elsevier
… , but their detection and characterization lagged. Several different nitrated fatty acid species
have been reported in animals and humans, but their formation remains controversial, and a …

n-3 Polyunsaturated fatty acids are associated with stable nitric oxide metabolites in highly trained athletes

AY Lyudinina, OI Parshukova, ER Bojko - Cells, 2024 - mdpi.com
… Conclusion: For the first time, the participation of essential n-3 PUFAs in the nitrite–nitrate
discussed; however, the exact mechanisms of action of fatty acids have not been described. …