[HTML][HTML] Nivolumab plus gemcitabine–cisplatin in advanced urothelial carcinoma

MS Van Der Heijden, G Sonpavde… - … England Journal of …, 2023 - Mass Medical Soc
… untreated patients with unresectable or metastatic urothelial carcinoma, … Nivolumab is an
antibody directed against programmed … of patients with locally advanced or metastatic urothelial

Nivolumab in patients with advanced platinum-resistant urothelial carcinoma: efficacy, safety, and biomarker analyses with extended follow-up from CheckMate 275

MD Galsky, A Saci, PM Szabo, GC Han… - Clinical Cancer …, 2020 - AACR
… evidence of metastatic or surgically unresectable, locally advanced urothelial carcinoma; …
metastatic disease were included. Additional eligibility criteria were reported previously (2). …

… Nivolumab plus gemcitabine-cisplatin versus gemcitabine-cisplatin alone for previously untreated unresectable or metastatic urothelial carcinoma: Results from the …

MS Van der Heijden, GP Sonpavde… - Annals of …, 2023 - annalsofoncology.org
… SOC) for cis-eligible patients (pts) with unresectable/metastatic urothelial carcinoma (mUC)
for decades… We report results for nivolumab (NIVO) plus gemcitabine-cis (GC) or GC alone in …

A Phase 2 Study of Sitravatinib in Combination with Nivolumab in Patients with Advanced or Metastatic Urothelial Carcinoma

P Msaouel, RF Sweis, M Bupathi, E Heath… - European Urology …, 2024 - Elsevier
… were ≥18 yr old with histologically confirmed UC with metastatic or unresectable, locally
advanced measurable disease (RECIST v1.1) and Eastern Cooperative Oncology Group …

Nivolumab+ Ipilimumab as Immunotherapeutic Boost in Metastatic Urothelial Carcinoma: A Nonrandomized Clinical Trial

MO Grimm, M Schostak, CB Grün, W Loidl… - JAMA …, 2024 - jamanetwork.com
… in previously untreated patients with unresectable, locally advanced or metastatic … using
nivolumab + ipilimumab as an immunotherapeutic boost for metastatic urothelial carcinoma? …

Phase I study of cabozantinib and nivolumab alone or with ipilimumab for advanced or metastatic urothelial carcinoma and other genitourinary tumors

AB Apolo, R Nadal, DM Girardi, SA Niglio… - Journal of Clinical …, 2020 - ascopubs.org
… , including cohorts for urothelial carcinoma, RCC, and other rare GU tumors with no standard
treatment options, and has also led to larger trials in GU tumors, including CheckMate 9ER (…

… II non-randomized clinical trial of nivolumab/ipilimumab maintenance following first-line chemotherapy in unresectable locally advanced or metastatic urothelial cancer …

G de Velasco, I García Carbonero, U Anido… - 2024 - ascopubs.org
Nivolumab (nivo) 1mg/kg plus ipilimumab (ipi) 3mg/kg achieved the highest ORR (42.4%)
in refractory metastatic urothelial carcinoma … in patients with unresectable urothelial cancer

Current status and future perspectives of immunotherapy for locally advanced or metastatic urothelial carcinoma: a comprehensive review

TJ Kim, KS Cho, KC Koo - Cancers, 2020 - mdpi.com
… CheckMate 275 was a single-arm phase II study of nivolumab in patients with platinum-refractory
metastatic UC [41]. The study endpoint was ORR in the overall group and the …

[HTML][HTML] Immunotherapy for Urothelial Carcinoma: Focus on Clinical Utility of Nivolumab

RS Chiang, MJ Glover, AR Khaki… - OncoTargets and …, 2022 - ncbi.nlm.nih.gov
… to the treatment landscape of bladder cancer. Nivolumab is an immune checkpoint inhibitor
… of platinum-refractory locally advanced or metastatic urothelial carcinoma. More recently, it …

Tailored immunotherapy approach with nivolumab with or without ipilimumab in patients with advanced transitional cell carcinoma after platinum-based chemotherapy …

MO Grimm, CB Grün, G Niegisch, M Pichler… - The Lancet …, 2023 - thelancet.com
… We aimed to examine the safety and activity of nivolumab … -line treatment for patients with
metastatic urothelial carcinoma. … in patients with locally advanced or metastatic urothelial