Psoriasis is an immune‐mediated systemic inflammatory disease that is not limited to the
skin but may be associated with arthritis, cardiovascular diseases, metabolic syndrome
including diabetes and obesity and, as identified more recently, non‐alcoholic fatty liver
disease (NAFLD) that occurs in approximately 50% of all patients with psoriasis. NAFLD is
characterized by accumulation of fat in hepatocytes in the absence of excessive alcohol
consumption. Over the last two decades, NAFLD has developed to the most common …

Nonalcoholic fatty liver disease (NAFLD) is a chronic progressive pathological condition that
ranges from simple hepatic steatosis to inflammatory-mediated steatohepatitis (NASH) and
that could further worsen to liver fibrosis, cirrhosis, liver failure, and hepatocellular
carcinoma. Psoriasis is currently described as a multisystemic disease that mainly affects
keratinocyte functions and of which abnormal autoimmune-like modulation leads to low-
grade chronic systemic inflammation easily transferred to the other organs. However, the link …