… In this review, we have described the most common noninvasive prenatal diagnosis … mRNA
expression is another way of screening for aneuploidies. Placenta-specific protein 4, located …

… accurate screening for fetal chromosomal aneuploidies in the … NIPT workflow for cell-free
fetal DNA (cffDNA) sequencing … Targeted ion semiconductor sequencing can perform NIPT …

… Noninvasive prenatal screening with cell-free DNA is now considered a first-line screening
for common aneuploidies. … interrogate the entirety of the fetal genome, and many commercial …

… Prenatal screening for Down syndrome is not compulsory in Iran. … require prenatal testing
of fetal aneuploidies were offered an alternative choice, either serum biochemical tests or NIPT. …

… In 2020, the American College of Obstetricians and Gynecologists (ACOG) stated that cfDNA
is the most sensitive and specific screening test for detecting common fetal aneuploidies […

… NIPT calculates the risk of fetal chromosomal aneuploidies … of semiconductor chips by the
semiconductor sequencing system. Then… sequencing platforms that are able to detect common …

… using semiconductor sequencing platform [n = 19,167] and BGI sequencing platform [n = …
Z ≥ 3 indicated a high risk of aneuploidy, z < 3 indicated low risk of aneuploidy, 1.96< z < 4 …

… Additional 500 digital analysis of selected regions (DANSR) assays, in comparison to
array-based NIPT for detecting common aneuploidies, were designed against targets uniformly …

… NIPS has been widely adopted for screening common chromosomal aneuploidies, such as
… -generation sequencing (NGS) technology [2]. However, the usefulness of cfDNA testing in …

… disorders, we prospectively applied the newly reported non-invasive prenatal sequencing
for … NIPS for detection of common aneuploidies has be facilitated after large-scale studies …