Circulating microRNA biomarkers in melanoma and non-melanoma skin cancer

G Durante, E Broseghini, F Comito… - Expert review of …, 2022 - Taylor & Francis
Introduction Skin cancer is the most common type of cancer and is classified in melanoma
and non-melanoma cancers, which include basal cell, squamous cell, and Merkel cell …

[HTML][HTML] The tumor and host immune signature, and the gut microbiota as predictive biomarkers for immune checkpoint inhibitor response in melanoma patients

K Tomela, B Pietrzak, M Schmidt, A Mackiewicz - Life, 2020 - mdpi.com
biomarkers of response to ICI melanoma therapies, their pre-treatment predictive values, and
their utility as on-treatment … specific, and optimized biomarkers of response to ICI therapies. …

Combining BRAF/MEK inhibitors with immunotherapy in the treatment of metastatic melanoma

DC Ziogas, F Konstantinou, S Bouros… - American Journal of …, 2021 - Springer
… of care for the management of BRAF-mutated melanoma but definitely provided further …
focused on immune biomarkers, are needed to optimize the upfront treatment strategy and …

Double trouble: immunotherapy doublets in melanoma—approved and novel combinations to optimize treatment in advanced melanoma

F Dimitriou, A Hauschild, JM Mehnert… - American Society of …, 2022 - ascopubs.org
… a standard of care for the treatment of patients with advanced melanoma. At present, …
for advanced melanoma; a phase II/III clinical trial of nivolumab combined with a novel anti-LAG3 …

[HTML][HTML] NRAS mutant melanoma: Towards better therapies

T Randic, I Kozar, C Margue, J Utikal, S Kreis - Cancer treatment reviews, 2021 - Elsevier
… available therapeutic options for NRAS mut melanoma patients … most promising novel
therapeutic approaches for melanoma … Subsequent efforts have focused on dose optimization and …

[HTML][HTML] Biomarker discovery and application—an opportunity to resolve the challenge of liver cancer diagnosis and treatment

J Chen, C Niu, N Yang, C Liu, S Zou, S Zhu - Pharmacological Research, 2023 - Elsevier
biomarkers involved in tumor development may become critical therapeutic targets for anti-tumor
therapy… Regarding the HLA allele, the survival rate of advanced melanoma patients with …

[HTML][HTML] Prediction of biomarkers and therapeutic combinations for anti-PD-1 immunotherapy using the global gene network association

CC Wu, YA Wang, JA Livingston, J Zhang… - Nature …, 2022 - nature.com
… correlation with patient response to anti-PD1 for 411 melanoma samples complied from 6
cohorts. Furthermore, mapping drug target data to the top genes in our association prediction …

Optimal treatment strategy for metastatic melanoma patients harboring BRAF-V600 mutations

EF Giunta, V De Falco, S Napolitano… - Therapeutic …, 2020 - journals.sagepub.com
… The optimization of treatment strategies with current drugs, the validation of promising …
agents will meaningfully improve, in the near future, the clinical management of these patients. …

[HTML][HTML] Recent advances in cancer plasticity: cellular mechanisms, surveillance strategies, and therapeutic optimization

GN Fanelli, AG Naccarato, C Scatena - Frontiers in Oncology, 2020 - frontiersin.org
… —may represent potential therapeutic targets of EMT: IL-6 … treatment with endostatin has
proved no effect on the inhibition of melanoma VM (148), thus portraying aggressive melanoma

[HTML][HTML] Regulation of LncRNAs in melanoma and their functional roles in the metastatic process

M Melixetian, PG Pelicci, L Lanfrancone - Cells, 2022 - mdpi.com
… promising drug targets and biomarkers in melanoma. … be functionalized and delivery optimized
by surface modification … proved to be promising drug targets or drug themselves in both …