[PDF][PDF] Unveiling the Preparation and Characterization of Lercanidipine Hydrochloride in an Oral Solid Self-Nanoemulsion for Enhancing Oral Delivery

HMA Hussein, MM Ghareeb, HA Hussein - Cureus, 2024 - cureus.com
… China) was utilized to examine the crystalline structure of pure LRCH and LRCH-SNEDDS …
system due to the solubilization effects of peppermint oil and Tween 20 which improved the …

Development, evaluation and optimization of solid self emulsifying drug delivery system (s-sedds) of lercanidipine hydrochloride

P Bhargavi, A Naha, S Kannan… - Research Journal of …, 2020 - indianjournals.com
… 1:9 we have selected 3 Oil: Smix ratios in which oil quantity is 20μL … shows the presence
of crystalline Lercanidipine HCl. But no such … A review on novel therapeutic strategies for the …

Exploratory Study on Lercanidipine Hydrochloride Polymorphism: pH-Dependent Solubility Behavior and Simulation of its Impact on Pharmacokinetics

IA Repin, R Loebenberg, J DiBella, ACL Conceição… - AAPS …, 2021 - Springer
… It also showcases the benefits of using PBPK simulations, to assess the risk and
pharmacokinetic relevance of different solubility and particle size between crystal forms, for diverse …

Development, optimization, in-vitro, and in-vivo evaluation of chitosan-inlayed nano-spanlastics encompassing lercanidipine HCl for enhancement of bioavailability

HA Bukhary, KM Hosny, WY Rizg, AA Alahmadi… - Journal of Drug Delivery …, 2024 - Elsevier
… with lercanidipine HCl (LER), a third-dihydropyridine calcium channel blocker (DHP-CCBs)
[5]. Lercanidipine is … of the Span 20 molecules was a chaotic liquid-crystalline state [66,67]. …

Insights into the Pivotal Role of Calcium Channel Blockers and Its Nanoformulations in the Management of Hypertension

S Grewal, S Singh, N Sharma, T Behl, IK Grewal… - BioNanoScience, 2023 - Springer
… drug delivery systems as novel drug delivery carrier system for … Nifedipine is yellow
crystalline powder which is insoluble in … After 1 to 3 h of administration, lercanidipine plasma …

[PDF][PDF] Self-nanoemulsifying drug delivery system of cilnidipine

MRP Rao, S Kulkarni, A Sonawane… - Indian J Pharm Educ …, 2021 - researchgate.net
oil–water interface through the mixed film layer of the Smix, with the formation of liquid crystalline
… Her fields of interest are solubility enhancement and novel drug delivery systems. She …

Novel delivery system used for oral bioavailability enhancement of poorly water soluble drugs

SK Lakavath - Journal of Drug Delivery and Therapeutics, 2020 - jddtonline.info
… in soft or hard gelatin shells and enclose fine generally stable oil−in−water (o/w) emulsions
… ., & Veerareddy, PR Oral self-emulsifying powder of lercanidipine hydrochloride: formulation …

[PDF][PDF] Enhancement of solubility and dissolution rate of poorly soluble drug nifedipine by solid sedds

S Bindhani, U Mohapatra, S Mohapatra… - Int. J. Drug Deliv …, 2020 - academia.edu
… The absence of the crystal structure proved that the aerosil 200 … Novel self-nanoemulsifying
drug delivery systems (SNEDDS… Oral self-emulsifying powder of lercanidipine hydrochloride: …

[PDF][PDF] Preparation, characterization and stability studies of solid self emulsifying drug delivery system of nifedipine

S Bindhani, S Mohapatra, RK Kar - Int J Appl Pharm, 2020 - academia.edu
… There was a complete absence of crystal structure which … Novel self-nano emulsifying drug
delivery systems (SNEDDS) … drug delivery systems of lercanidipine HCl using medium and …

[HTML][HTML] Solid self-nanoemulsifying drug delivery systems of nimodipine: development and evaluation

M Kumar, PA Chawla, A Faruk… - Future Journal of …, 2024 - fjps.springeropen.com
type of oil, and the volume of oil required to make the emulsion cloudy was recorded. The
combination of oil and surfactant that emulsified a maximum quantity (of oilcrystalline pattern of …