[HTML][HTML] Therapeutic potential of heterocyclic compounds targeting mitochondrial calcium homeostasis and signaling in alzheimer's disease and Parkinson's disease

V Tapias, P González-Andrés, LF Peña, A Barbero… - Antioxidants, 2023 - mdpi.com
… by regulating the tricarboxylic acid cycle (TCA) and glycolytic … and hippocampal brain regions
and platelets of patients [4,5]. … in cortical neurons of 3xTg-AD or APPsw mice [131]. An age-…

[HTML][HTML] NADPH and mitochondrial quality control as targets for a circadian-based fasting and exercise therapy for the treatment of Parkinson's disease

WM Curtis, WA Seeds, MP Mattson, PC Bradshaw - Cells, 2022 - mdpi.com
… matrix for beta-oxidation and ketone body synthesis. As part of … occurred in the hippocampus
of APP/PS1 AD model mice [84]. … glycolysis has been shown to improve PD symptoms in …

[HTML][HTML] Acetyl-CoA metabolism and histone acetylation in the regulation of aging and lifespan

PC Bradshaw - Antioxidants, 2021 - mdpi.com
therapies decrease systemic glucose levels and glycolytic … as fatty acids, ketone bodies,
and branched chain amino acids. … in HDAC2 levels in the mouse hippocampus with aging that …

[HTML][HTML] Ketogenic diet has a positive association with mental and emotional well-being in the general population

S Garner, E Davies, E Barkus, AK Kraeuter - Nutrition, 2024 - Elsevier
… from glycolysis to fatty acid use, providing the body and brain … in neurodegenerative diseases,
such as Alzheimer's disease [2… diet were also asked if they measured their levels of ketone

Nutrition and Substance-Use Disorder

A Afzal, Z Batool, S Sadir, S Haider - Nutrition and Psychiatric Disorders, 2022 - Springer
… by neuronal loss in hippocampus, mammillary body, and thalamus. … diet is also described
in SUD treatment. Ketosis is a condition in which brain and plasma levels of ketone bodies are …

认知障碍性疾病中线粒体稳态的最新评估方法

W You, Y Li, K Liu, X Mi, Y Li, X Guo, Z Li - 中国神经再生研究(英文版), 2024 - sjzsyj.com.cn
… decreased ATP levels and increased glycolytic production of ATP, … synthase kinase 3beta
in primary cultured hippocampalintermediates and amino acids in a 3xTgAD mouse model of …