[HTML][HTML] Doxorubicin-induced cardiotoxicity: An update on the molecular mechanism and novel therapeutic strategies for effective management
PS Rawat, A Jaiswal, A Khurana, JS Bhatti… - Biomedicine & …, 2021 - Elsevier
… the cardioprotective action via reducing the Dox induces apoptosis. However, in miR21,
deficient species of rat shows cardiotoxic effects after Dox treatment. Cardioprotective action via …
deficient species of rat shows cardiotoxic effects after Dox treatment. Cardioprotective action via …
Ubiquitin-like protein FAT10: A potential cardioprotective factor and novel therapeutic target in cancer
K Zhang, L Chen, Z Zhang, J Cao, L He, L Li - Clinica chimica acta, 2020 - Elsevier
… In this manuscript, we review some important biological roles of FAT10 in cardioprotection
and tumor promotion. FAT10 may be cardioprotective in ischemia and hypoxia through …
and tumor promotion. FAT10 may be cardioprotective in ischemia and hypoxia through …
[HTML][HTML] Targeting the endothelium to achieve cardioprotection
N Herrera-Zelada, U Zuñiga-Cuevas… - Frontiers in …, 2021 - frontiersin.org
… Novel therapeutic strategies to limit infarct size are required … Cardioprotection is a research
topic with significant … system with multiple therapeutic targets with cardioprotective potential. …
topic with significant … system with multiple therapeutic targets with cardioprotective potential. …
Discovery of new therapeutic redox targets for cardioprotection against ischemia/reperfusion injury and heart failure
… We also present and discuss potential targets for redox-based therapies that are either …
we review the role of oxidative stress and redox biochemistry as targets for cardioprotection. …
we review the role of oxidative stress and redox biochemistry as targets for cardioprotection. …
Promoting mitochondrial fusion in doxorubicin-induced cardiotoxicity: A novel therapeutic target for cardioprotection
C Maneechote, T Khuanjing, B Ongnok… - Clinical …, 2022 - portlandpress.com
… In the present study, we have investigated the cardioprotective properties of Mdivi-1 (fission
inhibitor) and M1 (fusion promoter) pertinent to their mitochondrial-targeted therapy in DOX-…
inhibitor) and M1 (fusion promoter) pertinent to their mitochondrial-targeted therapy in DOX-…
Recent updates on novel therapeutic targets of cardiovascular diseases
M Afzal - Molecular and Cellular Biochemistry, 2021 - Springer
… thought to have cardioprotective activity via stimulating … and explored for cardioprotective
activities, Ubiquinone … been studied and found to have a cardioprotective effect [62]. Carfilzomib …
activities, Ubiquinone … been studied and found to have a cardioprotective effect [62]. Carfilzomib …
[HTML][HTML] Targeting the microRNA-34a as a novel therapeutic strategy for cardiovascular diseases
CC Hua, XM Liu, LR Liang, LF Wang… - Frontiers in …, 2022 - frontiersin.org
… It has been reported that inhibition of miR-34a attenuates cardiomyocyte inflammation
induced by ICIs targeting KLF4 which has a cardioprotective effect. This result indicated that …
induced by ICIs targeting KLF4 which has a cardioprotective effect. This result indicated that …
… application of melatonin in the treatment of cardiovascular diseases: current evidence and new insights into the cardioprotective and cardiotherapeutic properties
MH Pourhanifeh, E Dehdashtian… - … Drugs and Therapy, 2022 - Springer
… gland, has various features that may contribute to its cardioprotective effects [5, 6]. The protective
… In this review we aim to point out therapeutic potentials of melatonin in the treatment of …
… In this review we aim to point out therapeutic potentials of melatonin in the treatment of …
Effect of hyperglycaemia and diabetes on acute myocardial ischaemia–reperfusion injury and cardioprotection by ischaemic conditioning protocols
C Penna, I Andreadou, M Aragno… - British journal of …, 2020 - Wiley Online Library
… Novel therapeutic strategies are required to protect the … heart is resistant to cardioprotective
strategies, although clinical … myocardial IRI and cardioprotection, experiments investigating …
strategies, although clinical … myocardial IRI and cardioprotection, experiments investigating …
[HTML][HTML] Novel therapeutic strategies to reduce reperfusion injury after acute myocardial infarction
A Schäfer, T König, J Bauersachs, M Akin - Current Problems in Cardiology, 2022 - Elsevier
… Here, we describe the current strategies to limit reperfusion injury and to improve post-AMI
outcomes such as systemic or intracoronary hypothermia, left-ventricular unloading, …
outcomes such as systemic or intracoronary hypothermia, left-ventricular unloading, …