… residues (CD6-YtoF) resulted, however, in a CD6 form that … This suggests that stimulatory
effectors may conceivably bind to … human and rat primary T cells, where we manipulated CD6 …

… Here, we address the function of CD6 by deleting the CD166-binding domain in vivo while
… at the T:APC interface and not solely determined by interactions with inhibitory effectors. …

… for T-cell proliferation and effector functions, including the T cell-… This study thus constitutes
the first clear evidence for a … ), rat anti-mouse IgG (Abcam) for detection of CD6 in MEM98 …

… cell division control protein 42 homolog cIAP … Finally, the effector functions of the T cell are
finely tuned by cytokine … CD5 and CD6 tune TCR signalling CD5 and CD6 molecules are …

… regulate signaling, delivered by CD6 during T cell activation. Based on the cytoplasmic
regions, the isoforms of CD6 … , the cytoplasmic domains of CD6 undergo hyperphosphorylation, …