[HTML][HTML] Obesity-related endothelial dysfunction: Moving from classical to emerging mechanisms
… on endothelial function by interfering with nitric oxide availability … may contribute to the
vasoconstriction induced by endogenous … vasoconstriction and reversed impaired NO-dependent …
vasoconstriction induced by endogenous … vasoconstriction and reversed impaired NO-dependent …
Endothelial dysfunction in obesity-induced inflammation: molecular mechanisms and clinical implications
… from the L-arginine by the synthesized endothelial nitric oxide … Nitric oxide is a potent
endothelium-derived vasodilator … signaling and impaired vascular endothelial elasticity …
endothelium-derived vasodilator … signaling and impaired vascular endothelial elasticity …
Endotheliopathy of obesity
JP Cooke - Circulation, 2020 - Am Heart Assoc
… is endothelium-derived nitric oxide (NO), a potent vasodilator … generation by the endothelium)
becomes impaired early in healthy … In this regard, NO promotes insulin-mediated glucose …
becomes impaired early in healthy … In this regard, NO promotes insulin-mediated glucose …
Obesity and endothelial function
M Kajikawa, Y Higashi - Biomedicines, 2022 - mdpi.com
… (eg, nitric oxide (NO), prostacyclin, and endothelium-derived … were found between flow-mediated
vasodilation (FMD) … endothelial dysfunction, and endothelial function is impaired …
vasodilation (FMD) … endothelial dysfunction, and endothelial function is impaired …
Endothelial nitric oxide synthase in the perivascular adipose tissue
AWC Man, Y Zhou, N Xia, H Li - Biomedicines, 2022 - mdpi.com
… increase in blood pressure can induce vasoconstriction due … PVAT, and affects vascular
remodeling in obese mice [123]. In … Akt mediates the activation of eNOS, leading to increased NO …
remodeling in obese mice [123]. In … Akt mediates the activation of eNOS, leading to increased NO …
Hyperhomocysteinemia and low folate and vitamin B12 are associated with vascular dysfunction and impaired nitric oxide sensitivity in morbidly obese patients
M Haloul, SJ Vinjamuri, D Naquiallah, MI Mirza… - Nutrients, 2020 - mdpi.com
… [40] reported an intact endothelial-independent forearm blood flow in … impaired NO-mediated
vasodilation as the primary pathogenesis in vascular dysfunction that accompanies obesity …
vasodilation as the primary pathogenesis in vascular dysfunction that accompanies obesity …
Vasodilator dysfunction in human obesity: established and emerging mechanisms
F Schinzari, M Tesauro, C Cardillo - Journal of Cardiovascular …, 2021 - journals.lww.com
… from endothelium is nitric oxide (NO), a potent vasodilator that … We have also observed that
ET A -mediated vasoconstriction is … Impaired vasodilator capacity has been reported in obese …
ET A -mediated vasoconstriction is … Impaired vasodilator capacity has been reported in obese …
Preserved β-adrenergic-mediated vasodilation in skeletal muscle of young adults with obesity despite shifts in cyclooxygenase and nitric oxide synthase
JK Limberg, RE Johansson, KJ Carter… - American Journal …, 2022 - journals.physiology.org
… -mediated vasodilation with obesity may augment total peripheral resistance, contributing
to impaired blood … exhibited a significant increase in Iso-mediated blood flow and vascular …
to impaired blood … exhibited a significant increase in Iso-mediated blood flow and vascular …
Endothelial and exercise vasodilation are reduced in postmenopausal females with obesity versus lean and overweight
… estimate primarily nitric oxide-mediated endothelial function [9… obesity impairs endothelial
function and exercise blood flow (… Examining markers in blood such as nitric oxide may have …
function and exercise blood flow (… Examining markers in blood such as nitric oxide may have …
The role of obesity-induced perivascular adipose tissue (PVAT) dysfunction in vascular homeostasis
A Stanek, K Brożyna-Tkaczyk, W Myśliński - Nutrients, 2021 - mdpi.com
… of the well-known vasodilator nitric oxide (NO) is increased. In … VSMCs are also known as a
target for leptin, which impairs the … -mediated vasodilation effects were reduced and led to an …
target for leptin, which impairs the … -mediated vasodilation effects were reduced and led to an …