Comparison of oleocanthal-low EVOO and oleocanthal against amyloid-β and related pathology in a mouse model of alzheimer's disease
… Astrocyte activation is recognized by increased glial fibrillary acidic protein (GFAP) with an …
astrocyte activation and ameliorated the astrocyte shape in mouse brains. Besides astrocytes …
astrocyte activation and ameliorated the astrocyte shape in mouse brains. Besides astrocytes …
Neuroprotective effects of oleocanthal in neurological disorders
YS Batarseh, SB Al Rihani, E Yang… - Olives and Olive Oil in …, 2021 - Elsevier
… Oleocanthal increased amyloid-β clearance by multiple pathways, … viability and rectified the
toxic effect of hydrogen peroxide–… of Aβ oligomers (Aβo) in neurons and astrocytes to further …
toxic effect of hydrogen peroxide–… of Aβ oligomers (Aβo) in neurons and astrocytes to further …
(-)-Oleocanthal nutraceuticals for Alzheimer's disease amyloid pathology: Novel oral formulations, therapeutic, and molecular insights in 5xFAD transgenic mice model
… a couple of defined pathways, amyloid-β (Aβ) and tau-related … distributed in brain neurons,
astrocytes, and microglia [13]. … Overall, both OC-PF and OC-SD treatments ameliorated the …
astrocytes, and microglia [13]. … Overall, both OC-PF and OC-SD treatments ameliorated the …
Olive oil diet and amyloidosis: focus on Alzheimer's disease
E Lauretti - Olives and Olive Oil in Health and Disease Prevention, 2021 - Elsevier
… the inhibition of amyloid β (Aβ) toxic fragment synthesis, … when oleocanthal is added to
neurons before Aβ oligomeric … also the consumption of EVOO ameliorate memory, cognitive …
neurons before Aβ oligomeric … also the consumption of EVOO ameliorate memory, cognitive …
Purified oleocanthal and ligstroside protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing
R Grewal, M Reutzel, B Dilberger, H Hein, J Zotzel… - Experimental …, 2020 - Elsevier
… Human Aβ 1–40 level in SH-SY5Y-APP 695 cells after 24 h incubation with EtOH as control,
oleocanthal or ligstroside. Cell were lysed and Aß levels were determined by ELISA, and …
oleocanthal or ligstroside. Cell were lysed and Aß levels were determined by ELISA, and …
(−)-Oleocanthal as a Nutraceutical for the Control of Breast Cancer and Amyloid Pathologies
A Tajmim - 2021 - search.proquest.com
… The confirmatory finding that oleocanthal is the sole irritating compound in EVOO was
achieved by quantifying oleocanthal from various EVOOs and measuring the throat irritation …
achieved by quantifying oleocanthal from various EVOOs and measuring the throat irritation …
Neuroprotection induced by olive oil components
TG Kezele, B Ćurko-Cofek - Natural Molecules in Neuroprotection and …, 2024 - Elsevier
… acids, protect cells from toxicity and alleviate inflammation and … Oleocanthal is a naturally
occurring phenolic secoiridoid … of astrocytes by preventing the effects of downregulation of Aβ-…
occurring phenolic secoiridoid … of astrocytes by preventing the effects of downregulation of Aβ-…
Natural therapeutics in aid of treating alzheimer's disease: a green gateway toward ending quest for treating neurological disorders
… with diseases progression ameliorates disease management… The identification of amyloid-β
as the principal constituent of … Overexpression of microglial cells and astrocytes promotes …
as the principal constituent of … Overexpression of microglial cells and astrocytes promotes …
Oleocanthal Ameliorates Metabolic and Behavioral Phenotypes in a Mouse Model of Alzheimer's Disease
… Sleep disorders may affect the circadian rhythm, which has been linked to fluctuations in
amyloid-β (Aβ) levels in interstitial brain fluid (ISF) and cerebrospinal fluid (CSF) [9,10,11,12]. In …
amyloid-β (Aβ) levels in interstitial brain fluid (ISF) and cerebrospinal fluid (CSF) [9,10,11,12]. In …
Use of olive oil polyphenols to counteract neuroinflammation and neurodegenerative diseases
D Di Risola - 2023 - iris.uniroma1.it
… toxic sAPPbeta, and a concomitant increase in the expression of synaptic proteins, reduced
astrocyte-associated and neuron-… These studies suggest that oleocanthal may be a potential …
astrocyte-associated and neuron-… These studies suggest that oleocanthal may be a potential …