Distinct relationships between risky decision making and cocaine self-administration under short-and long-access conditions

CA Orsini, SL Blaes, RJ Dragone, SM Betzhold… - Progress in neuro …, 2020 - Elsevier
… Based on these findings, it is conceivable that, if rats self-administered cocaine for 2 ha day
for 14 d, similar relationships between risk preference and escalation of intake would emerge…

Win-paired cues modulate the effect of dopamine neuron sensitization on decision making and cocaine self-administration: divergent effects across sex

TJ Hynes, CS Chernoff, KM Hrelja, TL Maric… - Biological …, 2024 - Elsevier
… Greater phasic DA activity has previously been observed in rats that were more hyperactive
in a novel environment and self-administered more cocaine (40). Likewise, chemogenetic …

The Effects of Escalated Cocaine Intake on Decision-making Dynamics

MA Stephens - 2021 - uknowledge.uky.edu
… between selfadministered cocaine and a species-specific non-drug alternative (money for
humans, food for rhesus monkeys and rats) showed a similar pattern of cocaine choice across …

[HTML][HTML] The subjective experience of heroin effects among individuals with chronic opioid use: Revisiting reinforcement in an exploratory study

S Martinez, L Brandt, SD Comer, FR Levin… - Addiction …, 2022 - Elsevier
… limited support for the opponent process theory, with less … support for the opponent process
theory which purports that … and methadone were self-administered at doses that produced …

Emergence of negative affect as motivation for drug taking in rats chronically self-administering cocaine

SD Klein, NJ Beacher, JM Kulik, DJ Estrin… - …, 2020 - Springer
… is rapidly rising) of self-administered cocaine and when given … opponent processes extends
beyond the self-administration session. It appears that after chronic long-access cocaine SA, …

Rapid appearance of negative emotion during oral fentanyl self‐administration in male and female rats

KR Coffey, WB Nickelson, AJ Dawkins… - Addiction …, 2023 - Wiley Online Library
… Oral fentanyl SA produced patterned SA similar to IV cocaine, … 10) rats were trained to
self-administered oral fentanyl 5 days a … that the affective opponent process can be detected even …

Investigating Dopaminergic and Opioidergic Mechanisms of Cocaine Conditioned Reinforcement Using the New Response Acquisition Procedure

L Rysztak - 2023 - deepblue.lib.umich.edu
properties of cocaine-paired cues. The New Response Acquisition procedure tests the ability
of cocaine… rats receive noncontingent infusions of cocaine either with simultaneous (Paired) …

Modeling features of addiction with an oral oxycodone self-administration paradigm

CA Murphy, YH Chang, R Pareta, JN Li, RA Slivicki… - bioRxiv, 2021 - biorxiv.org
… First, prescription opioids such as oxycodone are orally self-administered and … ,
cocaine, methamphetamine, or morphine), prescription opioids are most often orally self-administered: …

Extended access self-administration of methamphetamine is associated with age-and sex-dependent differences in drug taking behavior and recognition memory in …

SR Westbrook, MR Dwyer, LR Cortes… - Behavioural brain …, 2020 - Elsevier
… Our findings suggest that METH self-administered during adolescence impairs PFC-…
colleagues [29] reported opposing directions of effect of cocaine injections during adolescence on …

Cocaine and its variations in forms of presentation and addiction

AG de Castro Neto, M da Silva Figueiroa… - … An International and …, 2020 - books.google.com
… Intensity of effects, dependence, and craving are strongly influenced by the way in which
the drug is self-administered. Compulsive use, besides chemical dependence, can make …