Organoid technology for personalized pancreatic cancer therapy

A Bengtsson, R Andersson, J Rahm, K Ganganna… - Cellular Oncology, 2021 - Springer
Personalized medicine, or precision medicine, is an approach for improving the outcome of
cancer therapies … drug screening and personalized therapy in pancreatic cancer, utilizing the …

[HTML][HTML] Organoid factory: The recent role of the human induced pluripotent stem cells (hiPSCs) in precision medicine

G Novelli, P Spitalieri, M Murdocca… - Frontiers in Cell and …, 2023 - frontiersin.org
… This is an increasing trend that shed the light on the need of … with diagnosis, drug screening
and personalized treatment. … applications in regenerative medicine and cell therapy. However…

Human organoids: model systems for human biology and medicine

J Kim, BK Koo, JA Knoblich - Nature Reviews Molecular Cell Biology, 2020 - nature.com
… In summary, organoids constitute an improvement in the … as resources for regenerative
medicine coupled with genetic … -derived organoids in personalized medicine to provide robust …

[HTML][HTML] An organoids biobank for recapitulating tumor heterogeneity and personalized medicine

H Yang, N Zhang, YC Liu - Chinese Journal of Cancer Research, 2020 - ncbi.nlm.nih.gov
… and providing a Wnt niche for organoids to better mimic every stage of original tumor (24). …
tumor heterogeneity using organoids biobank and exploring personalized therapeutic

[HTML][HTML] Three-dimensional modelling of ovarian cancer: From cell lines to organoids for discovery and personalized medicine

C Yee, KA Dickson, MN Muntasir, Y Ma… - … in bioengineering and …, 2022 - frontiersin.org
cancer will improve the ability to recapitulate tumor heterogeneity. Three-dimensional (3D)
modelling systems, from cell lines to organoid or … personalized therapies for ovarian cancers. …

Hydrogel based tissue engineering and its future applications in personalized disease modeling and regenerative therapy

S Chaudhary, E Chakraborty - Beni-Suef University Journal of Basic and …, 2022 - Springer
… This review paper, focuses on discussing the novel organoid … Comparison between common
therapy and personalized therapy… , cancer research, regenerative medicine, stem cell study, …

Cancer spheroids and organoids as novel tools for research and therapy: state of the art and challenges to guide precision medicine

S El Harane, B Zidi, N El Harane, KH Krause, T Matthes… - Cells, 2023 - mdpi.com
customized therapy targeting ALDH1 could reduce resistance to chemotherapy and improve
the survival rate of ovarian cancer… to new therapies and regenerative medicine applications […

[PDF][PDF] Tumor organoids: Opportunities and challenges to guide precision medicine

V Veninga, EE Voest - Cancer Cell, 2021 - cell.com
… of tumor organoids and their potential relevance to improve … and potentially optimize
personalized therapy. Phan et al. … tumor organoids toward 240 kinase inhibitors and identified …

[HTML][HTML] Current challenges associated with the use of human induced pluripotent stem cell-derived organoids in regenerative medicine

H Lee, MY Son - International Journal of Stem Cells, 2021 - ncbi.nlm.nih.gov
to improve the organoid models, and how organoids can recapitulate mature organ systems
of the human body for regenerative medicine. … to develop personalized medicine for cystic …

Patient derived organoids in prostate cancer: Improving therapeutic efficacy in precision medicine

S Pamarthy, HE Sabaawy - Molecular Cancer, 2021 - Springer
… provide a reliable model to assess drug … personalized therapies for PCa. Owing to the
association of CSC with drug resistance and tumor relapse, we found that CSC-derived organoids