Origins, genomic structure and copy number variation of snake venom myotoxins

SS Gopalan, BW Perry, DR Schield, CF Smith… - Toxicon, 2022 - Elsevier
Crotamine, myotoxin a and homologs are short peptides that often comprise major fractions
of rattlesnake venoms and have been extensively studied for their bioactive properties.
These toxins are thought to be important for rapidly immobilizing mammalian prey and are
implicated in serious, and sometimes fatal, responses to envenomation in humans. While
high quality reference genomes for multiple venomous snakes are available, the loci that
encode myotoxins have not been successfully assembled in any existing genome assembly …
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