[HTML][HTML] Antifungal drug-resistance mechanisms in Candida biofilms

J Kaur, CJ Nobile - Current opinion in microbiology, 2023 - Elsevier
current knowledge of antifungal drug-resistance mechanisms occurring in Candida biofilms.
… The resistance and tolerance of fungal biofilms to standard antifungal drugs is complex and …

Aspergillus fumigatus biofilms: Toward understanding how growth as a multicellular network increases antifungal resistance and disease progression

KA Morelli, JD Kerkaert, RA Cramer - PLoS Pathogens, 2021 - journals.plos.org
… the multicellular filamentous fungal mycelium to fully understand its role in … our current
understanding of the form and function of A. fumigatus biofilms and identify key gaps in knowledge

Microbial biofilms in nature: unlocking their potential for agricultural applications

A Pandit, A Adholeya, D Cahill, L Brau… - Journal of applied …, 2020 - academic.oup.com
… explores the current understanding of naturally occurring microbial biofilms, and their
interaction with biotic surfaces, especially AMF. The possible roles played by bacterial biofilms and …

Candida albicans biofilms and polymicrobial interactions

NO Ponde, L Lortal, G Ramage, JR Naglik… - Critical reviews in …, 2021 - Taylor & Francis
… rates, making biofilm-associated infections a major clinical challenge. Here, we review the
current knowledge of the processes involved in C. albicans biofilm formation and development…

Candida Biofilms: An Update on Developmental Mechanisms and Therapeutic Challenges

PP de Barros, RD Rossoni, CM de Souza, L Scorzoni… - Mycopathologia, 2020 - Springer
yeast cells and/or pieces of the biofilm from its mature form. This allows for the circulation and
establishment of the biofilms … involved in the dispersion of cells from the biofilm [30, 56]. A …

Fungal biofilm architecture produces hypoxic microenvironments that drive antifungal resistance

CH Kowalski, KA Morelli, D Schultz… - Proceedings of the …, 2020 - National Acad Sciences
biofilms increases antifungal drug resistance. Our results define a previously unknown
mechanistic link between filamentous fungal biofilm physiology and contemporary antifungal drug …

Mechanistic Understanding of Candida albicans Biofilm Formation and Approaches for Its Inhibition

T Atriwal, K Azeem, FM Husain, A Hussain… - Frontiers in …, 2021 - frontiersin.org
biofilm. The e-DNA is present both in bacterial and fungal biofilms; hence, when these biofilm
with the respective drugs, they exhibit a decrease in the biofilm matrix (Martins et al., 2014). …

Combination therapy to treat fungal biofilm-based infections

J Tits, BPA Cammue, K Thevissen - International Journal of Molecular …, 2020 - mdpi.com
… literature regarding the combination of an antifungal with a non-antifungal, a so-called … of
the antifungal drug against fungal biofilms, and will leave combinations of antifungal drugs out …

Contributions of the Biofilm Matrix to Candida Pathogenesis

JE Nett, DR Andes - Journal of Fungi, 2020 - mdpi.com
biofilms and draw attention to the process of Candida-biofilm-matrix production. We provide
an update on the current understanding of how biofilm … roles in the promoting antifungal drug …

Biofilms in diabetic foot ulcers: significance and clinical relevance

C Pouget, C Dunyach-Remy, A Pantel, S Schuldiner… - Microorganisms, 2020 - mdpi.com
biofilm and act synergistically to cause a chronic infection. In this review, we … current
knowledge on biofilm formation, its presence in DFU, how the diabetic environment affects biofilm