… childhood ALL in large international cohorts [Citation4–6]. The prevalence and outcomes of
infant ALL, hypodiploid … , clinical features, and outcomes of infant ALL, hypodiploid ALL, and …

… The outcomes of pediatric acute lymphoblastic leukemia (ALL… “masked” hypodiploid ALL,
in which the hypodiploid clone is … mutations and the poor prognosis of hypodiploid ALL [37]. …

… further treatment stratification, patient management, and the clinical elucidation of outcome
… not aware of any hypodiploid and/or near-triploid ones with such a constellation [28, 32, 33]. …

… Children receiving HSCT for treatment of BCP-ALL with either hypodiploidy or bcr-abl1 fusion
showed outcomes comparable to BCP-ALL pts without these genetic lesions. CIR and EFS …

… subtype of childhood acute lymphoblastic leukaemia and is associated with a good outcome.
… All karyotypes were scrutinised for cases of masked hypodiploidy and, if found, were …

… in pediatric acute lymphoblastic leukemia. We aimed to characterize and study the prognostic
impact of hypodiploidy in pediatric … of poor outcome for OS in patients with hypodiploidy …

… B-ALL subtypes with less than 40 chromosomes, the current treatment protocols and their
clinical outcomes. Additionally, we discuss the potential cellular mechanisms involved on the …

… As we strive to improve outcomes for hypodiploid ALL, targeted immunotherapeutic approaches
could provide an alternative treatment strategy with increased benefit in these high-risk …

… Recently, in the results of a phase I study, 20 children and adults (aged 2–43 years) with
relapsed/remitting T-ALL were given allogeneic donor-derived anti-CD7 CAR-T-cells. …

… hypodiploid patients with low MRD after induction fare better (5-year EFS rates, 64%–75%),
their outcomes are still inferior to most children … -haploid and low-hypodiploid ALL appear to …