… The immature oocytes used in this study were all subjected to ovarian stimulation with high
… However, because ovarian aging occurs predominately at the primordial follicle stage, we …

… mitochondrial dysfunction may contribute to ovarian aging, and … mitochondrial pathways to
improve ovarian function in aging … in oocytes lead to impaired follicle development and oocyte …

… , acquiring new insights and knowledge about the mechanisms driving ovarian ageing is of
critical importance and this review describes how mitochondria contribute to oocyte ageing. …

… contribution of mitochondria to ovarian aging and reproductive … , we describe the role of
mitochondria in ovarian aging, as … an ovarian preovulatory follicle depicting the cumulus oocyte …

… Among these factors, we will consider mitochondria and … follicles and reduced ability to
produce oocytes competent for fertilization and embryo development. It is likely that ovary aging …

… key role of the mitochondria in preserving ovarian follicular … signalling pathways involved in
ovarian aging has been poorly … in mitochondrial number and function in oocytes and ovarian …

… analysis in in vitro matured oocytes, starting at the GV stage of an antral follicle and until 5 h
… currently are on “rescue IVM”, ie, the surplus immature oocytes from the controlled ovarian …

… In female mammals, mitochondrial function has been studied in … follicle, as well as in the
oocyte and developing embryo. During follicle development, mitochondria within the oocyte …

… the process of follicle development. As the follicle completes development, the oocyte resumes
… Furthermore, the huge excess of oocytes in the ovary at birth compared with the numbers …

… disruption; oxidative stress and mitochondrial damage. The aim … oocyte quality remain
unknown, the present review focuses on the potential role of ovarian follicle environment, oocyte …